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This study sought to assess TR frequency, management and outcome in this population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Among 6883 patients with severe native left-sided VHD or previous left-sided valvular intervention enrolled in the EURObservational Research Programme prospective VHD II survey, moderate or severe TR was very frequent in patients with severe mitral VHD (30% when mitral stenosis, 36% when mitral regurgitation [MR]), especially in patients with secondary MR (46%), and rare in patients with severe aortic VHD (4% when aortic stenosis, 3% when aortic regurgitation). An increase in TR grade was associated with a more severe clinical presentation and a poorer 6-month survival (p\u2009&amp;lt;\u20090.0001). Rates of concomitant tricuspid valve (TV) intervention at the time of left-sided heart valve surgery were high at the time of mitral valve surgery (50% when mitral stenosis, 41% when MR). Concordance between class I indications (patients with severe TR) for concomitant TV surgery at the time of left-sided valvular heart surgery according to guidelines and real-practice decision-making was very good (88% overall, 95% in patients operated on for MR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this large international prospective survey among patients with severe left-sided VHD, moderate\/severe TR was frequent in patients with mitral valve disease and was associated with a poorer outcome as TR grade increased. In patients with severe TR, compliance to guidelines for class I indications for concomitant TV surgery at the time of left-sided heart valve surgery was very good.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.3157","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:55:26Z","timestamp":1708390526000},"page":"994-1003","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Tricuspid Regurgitation: Frequency, Clinical Presentation, Management and Outcome Among Patients with Severe Left-Sided Valvular Heart Disease in Europe. Insights from the ESC-EORP Valvular Heart Disease II Survey"],"prefix":"10.1093","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1338-3007","authenticated-orcid":false,"given":"Julien","family":"Dreyfus","sequence":"first","affiliation":[{"name":"Cardiology Department, Centre Cardiologique du Nord , Saint-Denis ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Komar","sequence":"additional","affiliation":[{"name":"Department of Heart and Vessel Disease, Institute of Cardiology, Jagiellonian University Medical College , Krak\u00f3w ,","place":["Poland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Attias","sequence":"additional","affiliation":[{"name":"Cardiology Department, Centre Cardiologique du Nord , Saint-Denis ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"De Bonis","sequence":"additional","affiliation":[{"name":"Vita-Salute San Raffaele University , Milan ,","place":["Italy"]},{"name":"Department of Cardiac Surgery, IRCCS San Raffaele Hospital , Milan ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Ruschitzka","sequence":"additional","affiliation":[{"name":"Clinic of Cardiology, University Heart Centre, University Hospital , Zurich ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogdan A.","family":"Popescu","sequence":"additional","affiliation":[{"name":"University of Medicine and Pharmacy \u2018Carol Davila\u2019 \u2013 Euroecolab, Emergency Institute for Cardiovascular Diseases \u2018Prof. Dr. C.C. 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