{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:41:39Z","timestamp":1792813299668,"version":"4.5.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"},{"start":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T00:00:00Z","timestamp":1727136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Real-world data show that guidelines are insufficiently implemented, and particularly guideline-directed medical therapies (GDMT) are underused in patients with heart failure and reduced ejection fraction (HFrEF) in clinical practice. The Council for Cardiology Practice and the Heart Failure Association of the European Society of Cardiology (ESC) developed a survey aiming to (i) evaluate the perspectives of the cardiology community on the 2021 ESC heart failure (HF) guidelines, (ii) pinpoint disparities in disease management, and (iii) propose strategies to enhance adherence to HF guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>A 22-question survey regarding the diagnosis and treatment of HFrEF was delivered between March and June 2022. Of 457 physicians, 54% were general cardiologists, 19.4% were HF specialists, 18.9% other cardiac specialists, and 7.7% non-cardiac specialists. For diagnosis, 52.1% employed echocardiography and natriuretic peptides (NPs), 33.2% primarily used echocardiography, and 14.7% predominantly relied on NPs. The first drug class initiated in HFrEF was angiotensin-converting enzyme inhibitors\/angiotensin receptor\u2013neprilysin inhibitor (ACEi\/ARNi) (91.2%), beta-blockers (BB) (73.8%), mineralocorticoid receptor antagonists (MRAs) (53.4%), and sodium\u2013glucose cotransporter 2 (SGLT2) inhibitors (48.1%). The combination ACEi\/ARNi + MRA+ BB was preferred by 39.3% of physicians, ACEi\/ARNi + SGLT2 inhibitors + BB by 33.3%, and ACEi\/ARNi + BB by 22.2%. The time required to initiate and optimize GDMT was estimated to be &amp;lt;1\u2009month by 8.3%, 1\u20133\u2009months by 52%, 3\u20136\u2009months by 31.8%, and\u2009&amp;gt;6\u2009months by 7.9%. Compared to general cardiologists, HF specialists\/academic cardiologists reported lower estimated time-to-initiation, and more commonly preferred a parallel initiation of GDMT rather than a sequential approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Participants generally followed diagnostic and treatment guidelines, but variations in HFrEF management across care settings or HF specialties were noted. The survey may raise awareness and promote standardized HF care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.3444","type":"journal-article","created":{"date-parts":[[2024,9,25]],"date-time":"2024-09-25T00:15:36Z","timestamp":1727223336000},"page":"412-420","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Translating the 2021 ESC Heart Failure Guideline Recommendations in Daily Practice: Results from a Heart Failure Survey. A Scientific Statement of the ESC Council for Cardiology Practice and the Heart Failure Association of the ESC"],"prefix":"10.1093","volume":"27","author":[{"given":"Ruxandra","family":"Christodorescu","sequence":"first","affiliation":[{"name":"Department V Internal Medicine, University of Medicine and Pharmacy V. 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Iliescu\u2019 , Bucharest ,","place":["Romania"]},{"name":"University of Medicine and Pharmacy \u2018Carol Davila\u2019 , Bucharest ,","place":["Romania"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Ferrini","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Vascular Pathology, CH Saint Joseph and Saint Luc , Lyon ,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"K\u00fcmler","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Herlev-Gentofte University Hospital , Copenhagen ,","place":["Denmark"]},{"name":"Steno Diabetes Center Copenhagen , Herlev ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Toutoutzas","sequence":"additional","affiliation":[{"name":"First Department of Cardiology, Medical School, National and Kapodistrian University of Athens , Athens ,","place":["Greece"]},{"name":"\u201cHippokration\u201d General Hospital of Athens , Athens ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoni","family":"Bayes-Genis","sequence":"additional","affiliation":[{"name":"Institut del Cor, Hospital Universitari Germans Trias i Pujol, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Cardiovasculares (CIBERCV) , Barcelona ,","place":["Spain"]},{"name":"Departamento de Medicina, Universitat Aut\u00f2noma de Barcelona , Barcelona ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petar","family":"Seferovic","sequence":"additional","affiliation":[{"name":"University Medical Center, Medical Faculty University of Belgrade , Belgrade ,","place":["Serbia"]},{"name":"Serbian Academy of Sciences and Arts , Belgrade ,","place":["Serbia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Metra","sequence":"additional","affiliation":[{"name":"Cardiology, ASST Spedali Civili, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia , Brescia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ovidiu","family":"Chioncel","sequence":"additional","affiliation":[{"name":"Emergency Institute for Cardiovascular Diseases \u2018Prof. C.C. 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