{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:04:39Z","timestamp":1788307479701,"version":"build-2803163510"},"reference-count":108,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"vor","delay-in-days":377,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>During pregnancy, the maternal cardiovascular (CV) system undergoes major haemodynamic alterations ensuring adequate placental perfusion and a healthy pregnancy course. Hypertensive disorders of pregnancy (HDP) occur in almost 10% of gestations and preeclampsia, a more severe form, in 3\u20134%. Women with HDP demonstrated impaired myocardial function, biventricular chamber dysfunction and adverse biventricular remodelling. Shortly after delivery, women who experienced HDP express increased risk of classic CV risk factors such as hypertension, renal disease, abnormal lipid profile, and diabetes. Within the first two decades following a HDP, women experience increased rates of heart failure, chronic hypertension, ischaemic heart and cerebral disease. The mechanism underlying the relationship between HDP in younger women and CV disease later in life could be explained by sharing pre-pregnancy CV risk factors or due to a direct impact of HDP on the maternal CV system conferring a state of increased susceptibility to future metabolic or haemodynamic insults. Racial disparities in CV risk and social determinants of health also play an important role in their remote CV risk. Although there is general agreement that women who suffered from HDP should undertake early CV screening to allow appropriate prevention and timely treatment, a screening and intervention protocol has not been standardized due to limited available evidence. In this review, we discuss why women with hypertensive pregnancy may be disproportionately affected by heart failure with preserved ejection fraction and how cardiac remodelling during or after pregnancy may influence its development.<\/jats:p>","DOI":"10.1002\/ejhf.3520","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T02:40:12Z","timestamp":1732070412000},"page":"459-472","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Hypertensive Pregnancy Disorder, an Under-Recognized Women Specific Risk Factor for Heart Failure?"],"prefix":"10.1093","volume":"27","author":[{"given":"Chahinda","family":"Ghossein-Doha","sequence":"first","affiliation":[{"name":"Cardiovascular Institute, Thorax Center, Department of Cardiology, Erasmus Medical Center , Rotterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basky","family":"Thilaganathan","sequence":"additional","affiliation":[{"name":"Molecular and Clinical Sciences Research Institute, St. George's University of London , London ,","place":["UK"]},{"name":"Fetal Medicine Unit, Department of Obstetrics and Gynaecology, St George's University Hospitals NHS Foundation Trust , London ,","place":["UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur Jason","family":"Vaught","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine , Baltimore, MD ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan E.","family":"Briller","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine and Department of Obstetrics and Gynecology, University of Illinois Chicago , Chicago, IL ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jolien W.","family":"Roos-Hesselink","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute, Thorax Center, Department of Cardiology, Erasmus Medical Center , Rotterdam ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"2026010913024934100_ejhf3520-bib-0001","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/uog.17360","article-title":"Physiological adaptation of maternal plasma volume during pregnancy: A systematic review and meta-analysis","volume":"49","author":"de Haas","year":"2017","journal-title":"Ultrasound Obstet Gynecol"},{"key":"2026010913024934100_ejhf3520-bib-0002","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1002\/uog.17410","article-title":"Cardiac remodeling in normotensive pregnancy and in pregnancy complicated by 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