{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:13:52Z","timestamp":1790622832114,"version":"4.1.0"},"reference-count":74,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:00:00Z","timestamp":1451865600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,5,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Aortic stenosis (AS) is the most frequent degenerative valvular heart disease in Western countries and its prevalence increases in parallel with the ageing process of the population. Heart failure (HF), defined by the presence of reduced left ventricular ejection fraction, may be present in up to a quarter of patients with severe AS, posing diagnostic and management challenges. The present article reviews the prevalence of HF in severe AS patients, discusses the diagnostic challenges and the advances in multimodality imaging to identify the patients that may benefit from surgical or transcatheter aortic valve replacement, and summarizes the current evidence on management for this group of patients.<\/jats:p>","DOI":"10.1002\/ejhf.466","type":"journal-article","created":{"date-parts":[[2016,1,4]],"date-time":"2016-01-04T00:44:59Z","timestamp":1451868299000},"page":"469-481","source":"Crossref","is-referenced-by-count":33,"title":["Diagnosis and Management of Aortic Valve Stenosis in Patients with Heart Failure"],"prefix":"10.1093","volume":"18","author":[{"given":"Vasileios","family":"Kamperidis","sequence":"first","affiliation":[{"name":"Department of Cardiology, Heart and Lung Centrum, Leiden University Medical Centre , Albinusdreef 2, 2333 ZA, Leiden ,","place":["the Netherlands"]},{"name":"Department of Cardiology, AHEPA University Hospital , Thessaloniki ,","place":["Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Delgado","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart and Lung Centrum, Leiden University Medical Centre , Albinusdreef 2, 2333 ZA, Leiden ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas M.","family":"van Mieghem","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Thoraxcenter, Erasmus Medical Centre , Rotterdam ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arie-Pieter","family":"Kappetein","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery, Erasmus Medical Centre , Rotterdam ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin B.","family":"Leon","sequence":"additional","affiliation":[{"name":"Columbia University Medical Center and The Cardiovascular Research Foundation , New York, NY ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeroen J.","family":"Bax","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart and Lung Centrum, Leiden University Medical Centre , Albinusdreef 2, 2333 ZA, Leiden ,","place":["the Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2016,1,4]]},"reference":[{"key":"2026011721145251100_ejhf466-bib-0001","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0140-6736(06)69208-8","article-title":"Burden of valvular heart diseases: a population-based study","volume":"368","author":"Nkomo","year":"2006","journal-title":"Lancet"},{"key":"2026011721145251100_ejhf466-bib-0002","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A prospective survey of patients with valvular heart disease in Europe: The Euro 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