{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T18:52:27Z","timestamp":1769107947576,"version":"3.49.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T00:00:00Z","timestamp":1768867200000},"content-version":"vor","delay-in-days":4406,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>We hypothesized that diagnostic data in implantable devices evaluated on the day of discharge from a heart failure hospitalization (HFH) can identify patients at risk for HF readmission (HFR) within 30 days.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>In this retrospective analysis of four studies enrolling patients with CRT devices, we identified patients with a HFH, device data on the day of discharge, and 30-day post-discharge clinical follow-up. Four diagnostic criteria were evaluated on the discharge day: (i) intrathoracic impedance &amp;gt;8 \u03a9 below reference impedance; (ii) AF burden &amp;gt;6 h; (iii) CRT pacing &amp;lt;90%; and (iv) night heart rate &amp;gt;80 b.p.m. Patients were considered to have higher risk for HFR if \u22652 criteria were met, average risk if 1 criterion was met, and lower risk if no criteria were met. A Cox proportional hazards model was used to compare the groups. The data cohort consisted of a total of 265 HFHs in 175 patients, of which 36 (14%) were followed by HFR. On the discharge day, \u22652 criteria were met in 43 (16% of 265 HFHs), only 1 criterion was met in 92 (35%), and none of the four criteria were met in 130 HFHs (49%); HFR rates were 28, 16, and 7%, respectively. HFH with \u22652 criteria met was five times more likely to have HFR compared with HFH with no criteria met (adjusted hazard ratio 5.0; 95% confidence interval 1.9\u201313.5, P = 0.001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Device-derived diagnostic criteria evaluated on the day of discharge identified patients at significantly higher risk of HFR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.48","type":"journal-article","created":{"date-parts":[[2013,12,28]],"date-time":"2013-12-28T07:18:39Z","timestamp":1388215119000},"page":"419-425","source":"Crossref","is-referenced-by-count":18,"title":["Implantable Device Diagnostics on Day of Discharge Identify Heart Failure Patients at Increased Risk for Early Readmission for Heart Failure"],"prefix":"10.1093","volume":"16","author":[{"given":"Roy S.","family":"Small","sequence":"first","affiliation":[{"name":"The Heart Group of Lancaster General Health , 217 Harrisburg Avenue, Lancaster, PA, 17603 ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Whellan","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University , Philadelphia, PA ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Boyle","sequence":"additional","affiliation":[{"name":"Cleveland Clinic , Weston, FL ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shantanu","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Medtronic Inc. , Moundsview, MN ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodi","family":"Koehler","sequence":"additional","affiliation":[{"name":"Medtronic Inc. , Moundsview, MN ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo N.","family":"Warman","sequence":"additional","affiliation":[{"name":"Medtronic Inc. , Moundsview, MN ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William T.","family":"Abraham","sequence":"additional","affiliation":[{"name":"The Ohio State University , Columbus, OH ,","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2013,12,28]]},"reference":[{"key":"2026011921113344200_ejhf48-bib-0001","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1093\/eurjhf\/hfs105","article-title":"ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC","volume":"14","author":"McMurray","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"2026011921113344200_ejhf48-bib-0002","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1161\/CIRCHEARTFAILURE.109.885210","article-title":"Recent national trends in readmission rates after heart failure hospitalization","volume":"3","author":"Ross","year":"2010","journal-title":"Circ Heart Fail"},{"key":"2026011921113344200_ejhf48-bib-0003","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1056\/NEJMsa0803563","article-title":"Rehospitalizations among patients in the Medicare fee-for-service program","volume":"360","author":"Jencks","year":"2009","journal-title":"N Engl J Med"},{"key":"2026011921113344200_ejhf48-bib-0004","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1001\/jama.2012.216476","article-title":"Diagnoses and timing of 30-day readmissions after hospitalization for heart failure, acute myocardial infarction, or pneumonia","volume":"309","author":"Dharmarajan","year":"2013","journal-title":"JAMA"},{"key":"2026011921113344200_ejhf48-bib-0005","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/eurjhf\/hfq221","article-title":"European Society of Cardiology Heart Failure Association Standards for delivering heart failure care","volume":"13","author":"McDonagh","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"2026011921113344200_ejhf48-bib-0006","doi-asserted-by":"crossref","first-page":"606","DOI":"10.7326\/0003-4819-141-8-200410190-00008","article-title":"Care management for low-risk patients with heart failure: a randomized, controlled trial","volume":"141","author":"DeBusk","year":"2004","journal-title":"Ann Intern Med"},{"key":"2026011921113344200_ejhf48-bib-0007","doi-asserted-by":"crossref","first-page":"178","DOI":"10.7326\/0003-4819-150-3-200902030-00007","article-title":"A reengineered hospital discharge program to decrease rehospitalization: a randomized trial","volume":"150","author":"Jack","year":"2009","journal-title":"Ann Intern Med"},{"key":"2026011921113344200_ejhf48-bib-0008","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1161\/CIRCULATIONAHA.110.940262","article-title":"Improved outcomes with early collaborative care of ambulatory heart failure patients discharged from the emergency department","volume":"122","author":"Lee","year":"2010","journal-title":"Circulation"},{"key":"2026011921113344200_ejhf48-bib-0009","doi-asserted-by":"crossref","first-page":"2301","DOI":"10.1056\/NEJMoa1010029","article-title":"Telemonitoring in patients with heart failure","volume":"363","author":"Chaudhry","year":"2010","journal-title":"N Engl J Med"},{"key":"2026011921113344200_ejhf48-bib-0010","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/eurjhf\/hfr144","article-title":"Effect of a telemonitoring-facilitated collaboration between general practitioner and heart failure clinic on mortality and rehospitalization rates in severe heart failure: the TEMA-HF 1 (TElemonitoring in the MAnagement of Heart Failure) study","volume":"14","author":"Dendale","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"2026011921113344200_ejhf48-bib-0011","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1161\/CIRCULATIONAHA.104.492207","article-title":"Intrathoracic impedance monitoring in patients with heart failure: correlation with fluid status and feasibility of early warning preceding hospitalization","volume":"112","author":"Yu","year":"2005","journal-title":"Circulation"},{"key":"2026011921113344200_ejhf48-bib-0012","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1111\/j.1751-7133.2011.00220.x","article-title":"Superior Performance of intrathoracic impedance-derived fluid index versus daily weight monitoring in heart failure patients: results of the Fluid Accumulation Status Trial (FAST)","volume":"17","author":"Abraham","year":"2011","journal-title":"Congest Heart Fail"},{"key":"2026011921113344200_ejhf48-bib-0013","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.ahj.2012.06.020","article-title":"Burden of atrial fibrillation and poor rate control detected by continuous monitoring and the risk for heart failure hospitalization","volume":"164","author":"Sarkar","year":"2012","journal-title":"Am Heart J"},{"key":"2026011921113344200_ejhf48-bib-0014","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1161\/01.CIR.0000139841.42454.78","article-title":"Model 8042 and Attain OTW Lead Model 4193 Clinical Trial Investigators. Continuous autonomic assessment in patients with symptomatic heart failure: prognostic value of heart rate variability measured by an implanted cardiac resynchronization device","volume":"110","author":"Adamson","year":"2004","journal-title":"Circulation"},{"key":"2026011921113344200_ejhf48-bib-0015","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1016\/j.jacc.2009.11.089","article-title":"Combined heart failure device diagnostics identify patients at higher risk of subsequent heart failure hospitalizations: results from PARTNERS HF (Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure) study","volume":"55","author":"Whellan","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"2026011921113344200_ejhf48-bib-0016","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/eurjhf\/hfr089","article-title":"Potential value of automated daily screening of cardiac resynchronization therapy defibrillator diagnostics for prediction of major cardiovascular events: results from Home-CARE (Home Monitoring in Cardiac Resynchronization Therapy) study","volume":"13","author":"Sack","year":"2011","journal-title":"Eur J Heart Fail"},{"key":"2026011921113344200_ejhf48-bib-0017","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1093\/eurheartj\/eht083","article-title":"Development and validation of an integrated diagnostic algorithm derived from parameters monitored in implantable devices for identifying patients at risk for heart failure hospitalization in an ambulatory setting","volume":"34","author":"Cowie","year":"2013","journal-title":"Eur Heart J"},{"key":"2026011921113344200_ejhf48-bib-0018","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.amjcard.2012.08.050","article-title":"Development of a method to risk stratify patients with heart failure for 30-day readmission using implantable device diagnostics","volume":"111","author":"Whellan","year":"2013","journal-title":"Am J Cardiol"},{"key":"2026011921113344200_ejhf48-bib-0019","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1016\/j.jacc.2010.12.012","article-title":"The CONNECT (Clinical Evaluation of Remote Notification to Reduce Time to Clinical Decision) trial: the value of wireless remote monitoring with automatic clinician alerts","volume":"57","author":"Crossley","year":"2011","journal-title":"J Am Coll Cardiol"},{"key":"2026011921113344200_ejhf48-bib-0020","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.cardfail.2009.01.012","article-title":"Changes in intrathoracic impedance are associated with subsequent risk of hospitalizations for acute decompensated heart failure: clinical utility of implanted device monitoring without a patient alert","volume":"15","author":"Small","year":"2009","journal-title":"J Card Fail"},{"key":"2026011921113344200_ejhf48-bib-0021","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.jacc.2003.09.044","article-title":"Predischarge B-type natriuretic peptide assay for identifying patients at high risk of re-admission after decompensated heart failure","volume":"43","author":"Logeart","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"2026011921113344200_ejhf48-bib-0022","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ahj.2010.03.033","article-title":"Associations between worsening renal function and 30-day outcomes among Medicare beneficiaries hospitalized with heart failure","volume":"160","author":"Patel","year":"2010","journal-title":"Am Heart J"},{"key":"2026011921113344200_ejhf48-bib-0023","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1093\/eurheartj\/ehp144","article-title":"Weight changes after hospitalization for worsening heart failure and subsequent re-hospitalization and mortality in the EVEREST trial","volume":"30","author":"Blair","year":"2009","journal-title":"Eur Heart J"},{"key":"2026011921113344200_ejhf48-bib-0024","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.cardfail.2003.12.007","article-title":"The impact of arrhythmias in acute heart failure","volume":"10","author":"Benza","year":"2004","journal-title":"J Card Fail"},{"key":"2026011921113344200_ejhf48-bib-0025","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1161\/01.CIR.0000141562.22216.00","article-title":"Randomized, controlled evaluation of short- and long-term benefits of heart failure disease management within a diverse provider network: the SPAN-CHF trial","volume":"110","author":"Kimmelstiel","year":"2004","journal-title":"Circulation"},{"key":"2026011921113344200_ejhf48-bib-0026","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/j.jacc.2005.01.050","article-title":"Noninvasive home telemonitoring for patients with heart failure at high risk of recurrent admission and death: the Trans-European Network-Home-Care Management System (TEN-HMS) study","volume":"45","author":"Cleland","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2026011921113344200_ejhf48-bib-0027","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.jacc.2007.10.061","article-title":"Randomized controlled trial of an implantable continuous hemodynamic monitor in patients with advanced heart failure: the COMPASS-HF study","volume":"51","author":"Bourge","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"2026011921113344200_ejhf48-bib-0028","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1161\/CIRCULATIONAHA.111.043042","article-title":"Intrathoracic impedance monitoring, audible patient alerts, and outcome in patients with heart failure","volume":"124","author":"van Veldhuisen","year":"2011","journal-title":"Circulation"},{"key":"2026011921113344200_ejhf48-bib-0029","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/S0140-6736(11)60101-3","article-title":"Wireless pulmonary artery haemodynamic monitoring in chronic heart failure: a randomised controlled trial","volume":"377","author":"Abraham","year":"2011","journal-title":"Lancet"},{"key":"2026011921113344200_ejhf48-bib-0030","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.cardfail.2004.02.011","article-title":"Risk stratification after hospitalization for decompensated heart failure","volume":"10","author":"Felker","year":"2004","journal-title":"J Card Fail"}],"container-title":["European Journal of Heart Failure"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fejhf.48","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejhf.48","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ejhf.48","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/16\/4\/419\/66434857\/eurjhf_16_4_419.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/eurjhf\/article-pdf\/16\/4\/419\/66434857\/eurjhf_16_4_419.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:12:58Z","timestamp":1768875178000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/eurjhf\/article\/16\/4\/419\/8427781"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,28]]},"references-count":30,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2013,12,28]]},"published-print":{"date-parts":[[2014,4,1]]}},"URL":"https:\/\/doi.org\/10.1002\/ejhf.48","relation":{},"ISSN":["1388-9842","1879-0844"],"issn-type":[{"value":"1388-9842","type":"print"},{"value":"1879-0844","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2014,4]]},"published":{"date-parts":[[2013,12,28]]}}}