{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T17:05:26Z","timestamp":1768928726489,"version":"3.49.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T00:00:00Z","timestamp":1392681600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the prognostic impact of QRS width in patients with low-flow\/low-gradient aortic stenosis (LF\/LGAS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and results<\/jats:title>\n                    <jats:p>Among 88 consecutive patients referred to our institution for LF\/LGAS from September 1994 to March 2007, baseline demographic, clinical, echocardiographic, and electrocardiographic data were collected. This population was divided into two groups according to baseline QRS duration (cut-off QRS \u2265130\u2009ms). Follow-up data, including electrocardiographic evolution and overall mortality, were analysed. The mean follow-up duration was 3.1 (2.2\u20136.2) years. In the whole group, 67 patients underwent surgical aortic valve replacement. Forty-nine patients (56%) had a QRS duration \u2265130\u2009ms. Among operated patients, there was no significant change in QRS duration between baseline and latest follow-up (126\u2009\u00b1\u200926\u2009ms vs. 131\u2009\u00b1\u200925\u2009ms; P\u2009=\u20090.82). In addition, wider QRS was a strong independent predictor of overall mortality (hazard ratio 2.20, 95% confidence interval 1.15\u20134.24; P\u2009=\u20090.027).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Significant intraventricular conduction disturbances are common in patients with LF\/LGAS and do not recover after aortic valve replacement. QRS duration is strongly associated with mortality in this selected population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejhf.63","type":"journal-article","created":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T13:40:59Z","timestamp":1392730859000},"page":"639-647","source":"Crossref","is-referenced-by-count":14,"title":["Prevalence and Clinical Impact of QRS Duration in Patients with Low-Flow\/Low-Gradient Aortic Stenosis Due to Left Ventricular Systolic Dysfunction"],"prefix":"10.1093","volume":"16","author":[{"given":"Fr\u00e9d\u00e9ric A.","family":"Sebag","sequence":"first","affiliation":[{"name":"Department of Cardiology, Henri Mondor Hospital (Assistance Publique-H\u00f4pitaux de Paris) , Creteil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Lellouche","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Henri Mondor Hospital (Assistance Publique-H\u00f4pitaux de Paris) , Creteil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najia","family":"Chaachoui","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Henri Mondor Hospital (Assistance Publique-H\u00f4pitaux de Paris) , Creteil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Luc","family":"Dubois-Rande","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Henri Mondor Hospital (Assistance Publique-H\u00f4pitaux de Paris) , Creteil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pascal","family":"Gueret","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Henri Mondor Hospital (Assistance Publique-H\u00f4pitaux de Paris) , Creteil ,","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-Luc","family":"Monin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Henri 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