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The PEC on day 1 after the infection consisted of 48% macrophages and 50% lymphocytes, most of which were surface IgM<jats:sup>+<\/jats:sup> (B) cells. The number of PEC increased to the maximal level by day 3. The PEC at this stage contained an appreciable number of CD3<jats:sup>+<\/jats:sup> T cells in addition to a large number of macrophages. Of the CD3<jats:sup>+<\/jats:sup> cells, the proportion of CD4<jats:sup>\u2212<\/jats:sup>CD8<jats:sup>\u2212<\/jats:sup> cells, most of which expressed no TcR \u03b1\/\u03b2, increased to the maximal level on day 3 after the infection. In correlation with an increased number of CD3<jats:sup>+<\/jats:sup>CD4<jats:sup>\u2212<\/jats:sup>CD8<jats:sup>\u2212<\/jats:sup>TcR \u03b1\/\u03b2<jats:sup>\u2212<\/jats:sup> cells, high level of TcR \u03b3\/\u03b4 chain gene messages was detected in the nonadherent population of the PEC on this stage. On the other hand, the PEC on day 8 contained an increased number of CD4<jats:sup>+<\/jats:sup>CD8<jats:sup>\u2212<\/jats:sup> and CD4<jats:sup>\u2212<\/jats:sup>CD8<jats:sup>+<\/jats:sup> cells which expressed TcR \u03b1\/\u03b2 chain on their surface. These results suggest that the \u03b3\/\u03b4 T cells precede the \u03b1\/\u03b2 T cells in appearance during listerial infection. The \u03b3\/\u03b2 T cells may be involved at the first line of the host\u2010defense against <jats:italic>Listeria<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/eji.1830200311","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T11:47:25Z","timestamp":1172749645000},"page":"533-538","source":"Crossref","is-referenced-by-count":100,"title":["Sequential appearance of \u03b3\/\u03b4\u2010 and \u03b1\/\u03b2\u2010bearing T cells in the peritoneal cavity during an i.p. infection with <i>Listeria monocytogenes<\/i>"],"prefix":"10.1002","volume":"20","author":[{"given":"Shouichi","family":"Ohga","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasunobu","family":"Yoshikai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Hiromatsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kikuo","family":"Nomoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,17]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"141","volume":"138","author":"Kaufmann S. 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