{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T13:10:04Z","timestamp":1720703404835},"reference-count":14,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2005,11,17]],"date-time":"2005-11-17T00:00:00Z","timestamp":1132185600000},"content-version":"vor","delay-in-days":5618,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Immunol"],"published-print":{"date-parts":[[1990,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In order to elucidate the role of anti\u2010thyroglobulin (Tg) autoantibodies (A\u2010Ab) in experimental autoimmune thyroiditis (EAT), a kinetic study was conducted in EAT\u2010susceptible (CBA\/J) and non\u2010susceptible (C57BL\/6) strains of mice. From day 0 to 70 post\u2010Tg immunization, titers of A\u2010Ab to Tg and to the linear 5\u201010\u2010kDa Tg tryptic fragment inducing EAT as well as anti\u2010idiotypic A\u2010Ab representing the internal image of the thyroidogeneic antigen were measured.<\/jats:p><jats:p>EAT onset, development and recovery correlate with the presence of two subsets of A\u2010Ab only in susceptible strains of mice. First, with the presence of anti\u2010Tg A\u2010Ab to one determinant borne by the linear 5\u201010\u2010kDa Tg tryptic fragment, and second with the presence of anti\u2010idiotypic A\u2010Ab specific for the monoclonal anti\u2010Tg A\u2010Ab (3B8G9) paratope which binds to Tg determinant inducing EAT.<\/jats:p>","DOI":"10.1002\/eji.1830200719","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T12:08:21Z","timestamp":1172750901000},"page":"1535-1539","source":"Crossref","is-referenced-by-count":14,"title":["Autoantibody specific for a thyroglobulin epitope inducing experimental autoimmune thyroiditis or its anti\u2010idiotype correlates with the disease"],"prefix":"10.1002","volume":"20","author":[{"given":"Ha\u00efwen","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Bedin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9atrice","family":"Texier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannine","family":"Charreire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,17]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60656-2"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830170617"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.174.4014.1137"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00364266"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830120512"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.4049\/jimmunol.138.4.1092","volume":"138","author":"Romball C. 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