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The patterns of migration of these two major lymphocyte subpopulations were distinctly different. While T cells seemed to migrate out of existing, flat endothelium\u2010lined blood vessels resulting in a diffuse distribution at the sites of inflammation, B cells were characteristically present as clusters of tightly packed cells at restricted sites in the inflamed tissue. Within these B cell clusters distinct capillary vessels lined with plumb endothelial cells were always present suggesting that they were the sites of intense migration of B cells originating from the draining lymph nodes. These results indicate differential regulation of adhesion molecules on B and T cells and\/or their ligands on endothelium during acute inflammatory reactions.<\/jats:p>","DOI":"10.1002\/eji.1830210940","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T13:01:49Z","timestamp":1172754109000},"page":"2269-2272","source":"Crossref","is-referenced-by-count":17,"title":["Differential migration of T and B cells during an acute inflammatory response"],"prefix":"10.1002","volume":"21","author":[{"given":"Chee\u2010Seong","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Els","family":"Meeusen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malcolm","family":"Brandon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,22]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(86)90832-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.05.040187.001221"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1989.tb00010.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"844","DOI":"10.4049\/jimmunol.128.2.844","volume":"128","author":"Stevens S. 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