{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T16:05:18Z","timestamp":1765728318806},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2005,11,17]],"date-time":"2005-11-17T00:00:00Z","timestamp":1132185600000},"content-version":"vor","delay-in-days":4795,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Immunol"],"published-print":{"date-parts":[[1992,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Surface immunoglobulin on mouse B cells is associated with a heterodimer comprising the products of the <jats:italic>mb\u20101<\/jats:italic> and B29 genes. Here we report that antibodies raised against a peptide sequence from the intracytoplasmic C terminus of the <jats:italic>B29<\/jats:italic> murine gene product detect the 37\u2010kDa component of the human heterodimer, indicating that this component in man is also encoded by the <jats:italic>B29<\/jats:italic> gene. The immunocytochemical reactivity of these anti\u2010B29 antibodies was compared with those of antibodies to the mb\u20101 protein. Of 25 cases of acute lymphoblastic leukaemia (ALL), 24 were positive for mb\u20101 whereas B29 was expressed in only 13 cases. Most of these B29\u2010positive ALL expressed immunoglobulin \u03bc heavy chain in their cytoplasm (pre\u2010B ALL). In lymphoid tissue sections, anti\u2010B29\u2010labeled B cell follicles in a similar fashion to anti\u2010mb\u20101, with the striking exception that plasma cells were unreactive for B29, but positive for mb\u20101. These results suggest that the synthesis of B29 begins later in precursor B cells than that of mb\u20101, and ceases before the terminal plasmacyte phase.<\/jats:p>","DOI":"10.1002\/eji.1830221044","type":"journal-article","created":{"date-parts":[[2007,3,1]],"date-time":"2007-03-01T13:13:36Z","timestamp":1172754816000},"page":"2753-2756","source":"Crossref","is-referenced-by-count":45,"title":["The B29 and mb\u20101 polypeptides are differentially expressed during human B cell differentiation"],"prefix":"10.1002","volume":"22","author":[{"given":"David Y.","family":"Mason","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carel J. M.","family":"Van Noesel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline L.","family":"Cordell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Marieke Comans\u2010Bitter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kingsley","family":"Micklem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albert G. D.","family":"Tse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ren\u00e9 A. W.","family":"Van Lier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacques J. M.","family":"Van Dongen4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,17]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1988.tb03219.x"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1988.tb03220.x"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1990.tb08129.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/343760a0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830201238"},{"key":"e_1_2_1_7_2","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.4049\/jimmunol.146.11.3881","volume":"146","author":"Van Noesel C. J. M.","year":"1991","journal-title":"J. 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