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Expression of this 777\u2010bp mRNA was restricted to dendritic cells and B cells, with strong expression in mature B cells. Southern blot analysis indicated that a single copy of this gene is present. <jats:italic>In situ<\/jats:italic> hybridization on tonsillar tissue showed expression in epithelial cells and isolated cells within the germinal center. With respect to an expressed\u2010sequence tag (EST) this cDNA could be localized to the major histocompatibility complex class I region of chromosome 6. Comparative analysis and the expression pattern of this gene suggests a function in antigen processing and presentation.<\/jats:p>","DOI":"10.1002\/eji.1830271002","type":"journal-article","created":{"date-parts":[[2007,3,2]],"date-time":"2007-03-02T04:08:42Z","timestamp":1172808522000},"page":"2471-2477","source":"Crossref","is-referenced-by-count":92,"title":["Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells"],"prefix":"10.1002","volume":"27","author":[{"given":"Elizabeth E. 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