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We demonstrate that TLR\u2010mediated responses are important in the innate immune response to LCMV and that MyD88 is essential for the control of the LCMV infection and the maturation\/activation of virus\u2010specific CD8<jats:sup>+<\/jats:sup> T\u2004cells.<\/jats:p>","DOI":"10.1002\/eji.200425730","type":"journal-article","created":{"date-parts":[[2005,2,22]],"date-time":"2005-02-22T09:48:46Z","timestamp":1109065726000},"page":"822-830","source":"Crossref","is-referenced-by-count":110,"title":["MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection"],"prefix":"10.1002","volume":"35","author":[{"given":"Shenghua","family":"Zhou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyn\u2004A.","family":"Kurt\u2010Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leisa","family":"Mandell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Cerny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melvin","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas\u2004T.","family":"Golenbock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert\u2004W.","family":"Finberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,22]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/35100529"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.21.120601.141126"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(02)00013-4"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1094351"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.20.083001.084359"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20031591"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.6.3415"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.2.533"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxh047"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-56055-2_6"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-56055-2_1"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.193.5.F19"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/362758a0"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.188.12.2205"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2004.01.033"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60197-2"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/369031a0"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.18.8407-8423.2001"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80469-0"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80470-7"},{"key":"e_1_2_7_21_2","doi-asserted-by":"crossref","first-page":"3713","DOI":"10.4049\/jimmunol.150.9.3713","article-title":"IFN induction and associated changes in splenic leukocyte distribution.","volume":"150","author":"Ishikawa R.","year":"1993","journal-title":"J. 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