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We used low frequencies of memory P14 T cells to demonstrate that T cells perform trogocytosis <jats:italic>in vivo<\/jats:italic> if in contact with APC pulsed with GP33\u2010peptide or expressing the antigen endogenously. Furthermore, <jats:italic>in vivo<\/jats:italic> trogocytosis of T cells is demonstrated during infections with lymphocytic choriomeningitis virus and vaccinia virus. Trogocytosis\u2010positive T cells revealed higher expression of activation marker and cytokines, showing a more activated phenotype compared to trogocytosis\u2010negative T cells.<\/jats:p>","DOI":"10.1002\/eji.201040743","type":"journal-article","created":{"date-parts":[[2010,10,13]],"date-time":"2010-10-13T11:49:22Z","timestamp":1286970562000},"page":"3450-3457","source":"Crossref","is-referenced-by-count":28,"title":["T cells acquire cell surface determinants of APC <i>via in vivo<\/i> trogocytosis during viral infections"],"prefix":"10.1002","volume":"40","author":[{"given":"Kerstin","family":"Rosenits","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selina J.","family":"Keppler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smiljka","family":"Vucikuja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Aichele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,11,15]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/ni0903-815"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(199904)29:04<1363::AID-IMMU1363>3.0.CO;2-0"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5441.952"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.2.875"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1084\/jem.191.7.1137"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.166.6.3645"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1006\/cimm.2001.1897"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.1.80"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(01)00234-5"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2020"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.9.5465"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.00916.x"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.12.7497"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-08-3236"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.2.830"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-09-047290"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-05-024547"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.126.4.1327"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.4.2271"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3083.2007.01996.x"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-04-1230"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2007.10.019"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0008489"}],"container-title":["European Journal of Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Feji.201040743","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/eji.201040743","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T15:38:31Z","timestamp":1697470711000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/eji.201040743"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,15]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["10.1002\/eji.201040743"],"URL":"https:\/\/doi.org\/10.1002\/eji.201040743","archive":["Portico"],"relation":{},"ISSN":["0014-2980","1521-4141"],"issn-type":[{"value":"0014-2980","type":"print"},{"value":"1521-4141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,11,15]]}}}