{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:33:27Z","timestamp":1785540807291,"version":"3.56.0"},"reference-count":42,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T00:00:00Z","timestamp":1498521600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB1158"],"award-info":[{"award-number":["SFB1158"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Neuropathic pain (NeuP) is a frequent sequel of spinal cord injury (<jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>). The <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> Pain Instrument (<jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content>) was developed as a <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>\u2010specific NeuP screening tool. A preliminary validation reported encouraging results requiring further evaluation in terms of psychometric properties. The pain<jats:styled-content style=\"fixed-case\">DETECT<\/jats:styled-content> questionnaire (<jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content>), a commonly applied NeuP assessment tool, was primarily validated in German, but not specifically developed for <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> and not yet validated according to current diagnostic guidelines. We aimed to provide convergent construct validity and to identify the optimal item combination for the <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content> was re\u2010evaluated according to current guidelines with respect to <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>\u2010related NeuP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective monocentric study. Subjects received a neurological examination according to the International Standards for Neurological Classification of <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>. After linguistic validation of the <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content>, the <jats:styled-content style=\"fixed-case\">IASP<\/jats:styled-content>\u2010grading system served as reference to diagnose NeuP, accompanied by the <jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content> after its re\u2010evaluation as binary classifier. Statistics were evaluated through <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>\u2010analysis, with the area under the <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content> curve (<jats:styled-content style=\"fixed-case\">AUROC<\/jats:styled-content>) as optimality criterion. The <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content> was refined by systematic item permutation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010eight individuals were assessed with the German <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content>. Of 127 possible combinations, a 4\u2010item\u2010<jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content> (cut\u2010off\u2010score\u00a0=\u00a01.5\/sensitivity\u00a0=\u00a00.864\/specificity\u00a0=\u00a00.839) was identified as most reasonable. The <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content> showed a strong correlation (r<jats:sub>sp<\/jats:sub>\u00a0=\u00a00.76) with <jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>\u2010analysis of <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">AUROC<\/jats:styled-content>\u00a0=\u00a00.877) revealed comparable results to <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">IASP<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">AUROC<\/jats:styled-content>\u00a0=\u00a00.916). <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>\u2010analysis of <jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content>\/<jats:styled-content style=\"fixed-case\">IASP<\/jats:styled-content> delivered a score threshold of 10.5 (sensitivity\u00a0=\u00a00.727\/specificity\u00a0=\u00a00.903).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The <jats:styled-content style=\"fixed-case\">SCIPI<\/jats:styled-content> is a valid easy\u2010to\u2010apply NeuP screening tool in <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>. The <jats:styled-content style=\"fixed-case\">PDQ<\/jats:styled-content> is recommended as complementary NeuP assessment tool in <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>, e.g. to monitor pain severity and\/or its time\u2010dependent course.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>In SCI\u2010related pain, both SCIPI and PainDETECT show strong convergent construct validity versus the current IASP\u2010grading system. SCIPI is now optimized from a 7\u2010item to an easy\u2010to\u2010apply 4\u2010item screening tool in German and English. We provided evidence that the scope for PainDETECT can be expanded to individuals with SCI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.1069","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T10:54:35Z","timestamp":1498560875000},"page":"1642-1656","source":"Crossref","is-referenced-by-count":21,"title":["Spinal Cord Injury Pain Instrument and pain<scp>DETECT<\/scp> questionnaire: Convergent construct validity in individuals with Spinal Cord Injury"],"prefix":"10.1002","volume":"21","author":[{"given":"S.","family":"Franz","sequence":"first","affiliation":[{"name":"Spinal Cord Injury Center Heidelberg University Hospital Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Schuld","sequence":"additional","affiliation":[{"name":"Spinal Cord Injury Center Heidelberg University Hospital Heidelberg 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