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A mixture of nociceptive and neuropathic pain (<jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content>) can present. Limited studies have investigated the impact of different pain phenotypes on quality of life (QoL) post\u2010<jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Members registered to a national support group for those with <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>s were surveyed (<jats:italic>n<\/jats:italic>\u00a0=\u00a01574). The survey comprised questions relating to demographics and <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> characteristics, The Douleur Neuropathique 4 (<jats:styled-content style=\"fixed-case\">DN<\/jats:styled-content>4) (interview), the International <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> Pain Basic Data Set recording the worst pain and the World Health Organisation Quality of Life <jats:styled-content style=\"fixed-case\">BREF<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">WHOQOL<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">BREF<\/jats:styled-content>). An <jats:styled-content style=\"fixed-case\">ANCOVA<\/jats:styled-content> model with post hoc analysis explored between group factors of pain type and intensity of pain categories on QoL, controlling for additional confounding variables. Significance was set <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05. A linear regression explored whether pain intensity, type or interference best predicted QoL.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The response rate was 41% (<jats:italic>n<\/jats:italic>\u00a0=\u00a0643), 70% (<jats:italic>n<\/jats:italic>\u00a0=\u00a0447) were male. The mean age of respondents was 52\u00a0years (SD 14.2) and mean time from <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content> was 17\u00a0years (SD 12.4). In the previous week, 71% (<jats:italic>n<\/jats:italic>\u00a0=\u00a0458) experienced pain, 37% (<jats:italic>n<\/jats:italic>\u00a0=\u00a0236) of which had <jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content> as defined in the study. Respondents experiencing <jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content> demonstrated significantly poorer QoL than those without pain (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) or nociceptive pain (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). Those reporting high pain intensity had significantly lower QoL than those with moderate or no pain (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001). Pain interference consistently and best\u2010predicted domains of QoL (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>High\u2010intensity pain and <jats:styled-content style=\"fixed-case\">NP<\/jats:styled-content> negatively impacts QoL post\u2010<jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>. However pain interference more than intensity or type best explains the variance in QoL reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Neuropathic pain type and severe pain intensities negatively impact <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content> after <jats:styled-content style=\"fixed-case\">SCI<\/jats:styled-content>. Pain interference items better predict reported QoL than either pain type or intensity, suggesting better pain management strategies are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.1248","type":"journal-article","created":{"date-parts":[[2018,5,17]],"date-time":"2018-05-17T06:04:45Z","timestamp":1526537085000},"page":"1662-1672","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":72,"title":["Quality of life after spinal cord injury: The impact of pain"],"prefix":"10.1002","volume":"22","author":[{"given":"D.","family":"Burke","sequence":"first","affiliation":[{"name":"UCD School of Public Health, Physiotherapy and Sports Science, Woodview House University College Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Lennon","sequence":"additional","affiliation":[{"name":"UCD School of Public Health, Physiotherapy and Sports Science, Woodview House University College Dublin 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