{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T21:28:09Z","timestamp":1780694889830,"version":"3.54.1"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,8,28]],"date-time":"2018-08-28T00:00:00Z","timestamp":1535414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Opioids are currently offered as first\u2010line treatment for chronic pain from cancer. Continuous regional analgesia could be an alternative to opioids. However, the required duration of catheterization and the sustained analgesic effects of this technique after catheter removal have yet to be clarified.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Report<\/jats:title><jats:p>We report the case of a patient with a shoulder desmoid tumour for which monitoring of tumour progression was the sole therapeutic strategy. Analgesia took the form of patient\u2010controlled infusion of local anaesthetics through an interscalene catheter. Due to the need of an <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> control 45\u00a0days later, the pump was stopped. The persistence of pain relief 48\u00a0hr later led to the decision to remove the perineural catheter. No pain was reported by the patient over the following 42\u00a0days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this patient, it would seem that continuous analgesia allowed for a sustained resolution of pain from the shoulder\u2010located tumour. One hypothesis is that local anaesthetics play a direct role in the erasure of pain memory. This hypothesis needs to be tested with a large patient cohort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>This case report provides new insights into the treatment of cancer pain. The most interesting finding is that the pain did remained absent after 45\u00a0days of continuous infusion of local anaesthetics through an interscalene catheter. We postulated that local anaesthetic drugs have an impact on pain memory.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.1295","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T05:24:46Z","timestamp":1533619486000},"page":"31-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A case report of sustained resolution of cancer pain by continuous perineural infusion of local anaesthetic"],"prefix":"10.1002","volume":"23","author":[{"given":"R\u00e9gis","family":"Fuzier","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Institut Claudius Regaud IUCT\u2010O Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Izard","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Institut Claudius Regaud IUCT\u2010O Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amelle","family":"Daboussi","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Institut Claudius Regaud IUCT\u2010O Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Pouymayou","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Institut Claudius Regaud IUCT\u2010O Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Pierre","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Institut Claudius Regaud IUCT\u2010O Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,28]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-12-04680.2000"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1140"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2008.11.012"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70040-2"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200211000-00030"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/15360288.2016.1192082"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00109-7"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-540-33823-9_13"},{"key":"e_1_2_7_10_1","first-page":"789","article-title":"Evidence of peripheral nerve blocks for cancer\u2010related pain: A systematic review","volume":"81","author":"Klepstad P.","year":"2015","journal-title":"Minerva Anestesiologica"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-8069-7-99"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X1003800324"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mjt.0000132250.95650.85"}],"container-title":["European Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fejp.1295","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejp.1295","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ejp.1295","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejp.1295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T13:39:52Z","timestamp":1694785192000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ejp.1295"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,28]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1002\/ejp.1295"],"URL":"https:\/\/doi.org\/10.1002\/ejp.1295","archive":["Portico"],"relation":{},"ISSN":["1090-3801","1532-2149"],"issn-type":[{"value":"1090-3801","type":"print"},{"value":"1532-2149","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,28]]},"assertion":[{"value":"2018-03-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-08-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}