{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T22:52:38Z","timestamp":1777071158125,"version":"3.51.4"},"reference-count":50,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,7,22]],"date-time":"2019-07-22T00:00:00Z","timestamp":1563753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pain descriptors capture the multidimensional nature of pain and can elucidate underlying pathophysiological mechanisms. This study determined whether the pain descriptors chosen by subjects experiencing acute dental pain associate with the outcomes of two commonly performed dental sensory tests. The goal of the study is to clarify whether pain descriptors are useful in discriminating the underlying biological processes contributing to dental pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Participants (<jats:italic>n<\/jats:italic>\u00a0=\u00a0228) presenting with acute toothache underwent standardized clinical dental sensory testing and described their pain in reference to 22 pain quality descriptors. Univariate and two\u2010way ANOVA determined the relationship between groups defined by cold detection (positive or negative) and percussion hypersensitivity (painful or not) on the affected tooth, and pain descriptor reporting.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Subjects experiencing painful toothache most frequently reported evoked pain to temperature and chewing, and pain descriptors such as \u201cthrobbing\u201d and \u201caching.\u201d They also reported neuropathic pain descriptors such as \u201ctingling\u201d and \u201celectric shock.\u201d Subjects who detected a cold stimulus (thermal) on the affected tooth, frequently reported high intensity paroxysmal shooting pain compared to those that did not detect cold. By contrast, patients with percussion (mechanical) hypersensitivity on the affected tooth, reported higher levels of global pain intensity at rest and in function, and reported significantly higher intensity \u201cradiating\u201d and \u201cthrobbing\u201d pain, than subjects with non\u2010painful percussion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The reporting of neuropathic pain descriptors by subjects experiencing acute toothache was more frequent than expected, suggesting that neuropathic mechanisms could contribute to typical toothache pain. Subjects experiencing toothache with mechanical hypersensitivity experience more intense pain overall.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>In subjects experiencing acute toothache, specific pain descriptors associate with the responses to routine clinical sensory tests performed on the injured tooth. The frequent reporting of neuropathic pain descriptors suggests that neuropathic mechanisms could create a diagnostic challenge to differentiate toothache from intraoral neuropathic conditions. Persons experiencing toothache with mechanical hypersensitivity experience more intense pain overall, suggesting patients with this clinical feature will have distinct clinical pain management needs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.1447","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T15:34:15Z","timestamp":1561563255000},"page":"1701-1711","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Sensory testing associates with pain quality descriptors during acute dental pain"],"prefix":"10.1002","volume":"23","author":[{"given":"Ozge","family":"Erdogan","sequence":"first","affiliation":[{"name":"Department of Endodontics New York University College of Dentistry New York New York"},{"name":"Department of Endodontics Faculty of Dentistry, Hacettepe University Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Malek","sequence":"additional","affiliation":[{"name":"Department of Endodontics New York University College of Dentistry New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malvin N.","family":"Janal","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Health Promotion New York University College of Dentistry New York New York"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Gibbs","sequence":"additional","affiliation":[{"name":"Department of Endodontics New York University College of Dentistry New York New York"},{"name":"Department of Restorative Dentistry and Biomaterials Sciences Harvard School of Dental Medicine Boston Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,7,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.06.001"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200003000-00012"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(00)00482-6"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2018.06.021"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.12.010"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1998.80.5.2621"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2011.0056"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1532-2149.2013.00377.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.09.012"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.08.004"},{"issue":"6","key":"e_1_2_7_12_1","first-page":"272","article-title":"Use of verbal descriptors, thermal scores and electrical pulp testing as predictors of tooth pain before and after application of benzocaine gels into cavities of teeth with pulpitis","volume":"36","author":"Gangarosa L. 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