{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:01:42Z","timestamp":1790190102110,"version":"4.1.0"},"reference-count":48,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,4,15]],"date-time":"2020-04-15T00:00:00Z","timestamp":1586908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["FL 156\/35\u20101"],"award-info":[{"award-number":["FL 156\/35\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["FL 156\/35-2"],"award-info":[{"award-number":["FL 156\/35-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["BE 5723\/1\u20102"],"award-info":[{"award-number":["BE 5723\/1\u20102"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Stress\u2010related dissociation has been shown to negatively co\u2010vary with pain perception in current borderline personality disorder (cBPD). While remission of the disorder (rBPD) is associated with normalized pain perception, it remains unclear whether dissociation proneness is still enhanced in this group and how this feature interacts with pain sensitivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010five cBPD patients, 20 rBPD patients and 24 healthy controls (HC) participated in an experiment using the script\u2010driven imagery approach. We presented a personalized stressful and neutral narrative. After listening to the scripts, dissociation and heat pain thresholds (HPT) were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Compared to HC, cBPD patients showed enhanced dissociation and exhibited significantly enhanced HPT in the neutral condition, whereas rBPD participants were in between. After listening to the stress script, both clinical groups exhibited enhanced dissociation scores. Current BPD participants responded with significantly higher HPT, whereas rBPD only showed a trend in the same direction. However, both BPD groups showed significantly increased HPT compared to the HC in the stress condition, but did not differ from each other. Dissociation proneness correlated significantly positively with pain hyposensitivity only in cBPD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dissociation proneness is enhanced in both BPD groups. This feature is clearly positively related to pain hyposensitivity in cBPD, but not in rBPD. However, the data indicate that stress causes the pain perception in rBPD to drift away from that obtained in HC. These results highlight the volatile state of BPD remission and might have important implications for the care of BPD patients in the remitted stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>Both current (cBPD) and remitted borderline personality disorder (rBPD) patients show enhanced proneness to dissociation. This feature is significantly linked with pain hyposensitivity in cBPD in a paradigm that induces stress using a script\u2010driven imagery approach, whereas this connection cannot be observed in rBPD. However, in the stress compared to the neutral condition, rBPD participants also show pain hyposensitivity compared to healthy controls. This study provides new insights into the pain processing mechanisms of BPD and its remission.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.1567","type":"journal-article","created":{"date-parts":[[2020,3,31]],"date-time":"2020-03-31T03:58:18Z","timestamp":1585627098000},"page":"1257-1268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Dissociation proneness and pain hyposensitivity in current and remitted borderline personality disorder"],"prefix":"10.1002","volume":"24","author":[{"given":"Boo Young","family":"Chung","sequence":"first","affiliation":[{"name":"Department of Cognitive and Clinical Neuroscience Medical Faculty Mannheim Central Institute of Mental Health Heidelberg University Mannheim Germany"},{"name":"Clinic of Anesthesiology and Intensive Care Medicine Pain Center Medical Faculty Mannheim Heidelberg University Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saskia","family":"Hensel","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy Medical Faculty Mannheim Central Institute of Mental Health University of Heidelberg Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilinca","family":"Schmidinger","sequence":"additional","affiliation":[{"name":"Department of General Psychiatry Center of Psychosocial Medicine University of Heidelberg Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Bekrater\u2010Bodmann","sequence":"additional","affiliation":[{"name":"Department of Cognitive and Clinical Neuroscience Medical Faculty Mannheim Central Institute of Mental Health Heidelberg University Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herta","family":"Flor","sequence":"additional","affiliation":[{"name":"Department of Cognitive and Clinical Neuroscience Medical Faculty Mannheim Central Institute of Mental Health Heidelberg University Mannheim Germany"},{"name":"Department of Health Science and Technology Center for Neuroplasticity and Pain (CNAP) SMI<sup>\u00ae<\/sup> Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_8_3_1","first-page":"1","article-title":"Wind\u2010up and neuroplasticity: Is there a correlation to clinical pain?","volume":"10","author":"Arendt\u2010Nielsen L.","year":"1995","journal-title":"European Journal of Anaesthesiology"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291711001917"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000275"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.12795"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(00)00179-7"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0005-7916(94)90063-9"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1504"},{"key":"e_1_2_8_10_1","volume-title":"Deutsche \u00dcbersetzung der Posttraumatic Stress Diagnostic Scale (PDS)","author":"Ehlers A.","year":"1996"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/eujp.1999.0154"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3758\/BRM.41.4.1149"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0020106"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/NMD.0b013e3181663026"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.10.028"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-017-0806-x"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8986.1979.tb01511.x"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.11.1920"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2005.03.026"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/15299732.2019.1678213"},{"key":"e_1_2_8_21_1","volume-title":"International personality disorder examination (IPDE): DSM\u2010IV and ICD\u201010 modules","author":"Loranger A. 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