{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T07:50:00Z","timestamp":1767340200803},"reference-count":27,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,5,31]],"date-time":"2020-05-31T00:00:00Z","timestamp":1590883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cervical dystonia is the most common form of focal idiopathic dystonia and is frequently associated with pain. Headaches are not considered to be more prevalent among patients presenting with cervical dystonia, and headaches attributed to craniocervical dystonia are considered to be a rare disorder, despite the lack of studies and clinical information regarding the subject.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To investigate the prevalence, characteristics and impact of headaches attributed to craniocervical dystonia in cervical dystonia patients receiving treatment with botulinum toxin type\u2010A (BoT\u2010A).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010four patients presenting with cervical dystonia were assessed before receiving their scheduled BoNT\u2010A injections and then again approximately 4 and 16\u00a0weeks after, regarding the clinical characteristics of their dystonia and headaches. Headaches were classified in accordance with the current International Classification of Headache Disorders. We used the Short Form\u201036 Health Survey, Hospital Anxiety and Depression Scale, Headache Impact Test\u20106, Toronto Western Spasmodic Torticollis Rating Scale and McGill Pain Questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Nineteen patients (79.1%) presented with cervical dystonia associated with pain and 18 (75.0%) with headaches. The prevalence of headaches attributed to craniocervical dystonia was 29.2%; HIT\u20106: 60.1\u00a0\u00b1\u00a09.9. Patients with headaches presented significantly poorer TWSTRS pain scores, compared to patients with no headaches. Those with headaches attributed to craniocervical dystonia presented with more disability and demonstrated a significant improvement in the impact of headaches after BoNT\u2010A injections, together with an improvement in the dystonia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Headaches are highly prevalent amongst cervical dystonia patients, have an impact on their quality of life and improves after BoNT\u2010A injections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>We found that headaches are more frequent among patients with cervical dystonia than previously thought, and that they contribute towards an overall increase in pain in these patients. Headaches attributed to craniocervical dystonia are associated with greater disability among patients with cervical dystonia. These headaches improve after botulinum toxin injections, in parallel with the improvement of cervical dystonia symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.1601","type":"journal-article","created":{"date-parts":[[2020,5,18]],"date-time":"2020-05-18T23:31:46Z","timestamp":1589844706000},"page":"1484-1494","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Headache attributed to craniocervical dystonia: A prospective cohort study"],"prefix":"10.1002","volume":"24","author":[{"given":"Marcos","family":"Eugenio Ramalho Bezerra","sequence":"first","affiliation":[{"name":"Hospital das Cl\u00ednicas Universidade Federal de Pernambuco (UFPE) Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro A.","family":"Sampaio Rocha\u2010Filho","sequence":"additional","affiliation":[{"name":"Department of Neuropsychiatry Universidade Federal de Pernambuco (UFPE) Recife Brazil"},{"name":"Headache Clinic Hospital Universitario Oswaldo Cruz Universidade de Pernambuco (UPE) Recife Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,31]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000156909.13677.FF"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12996"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-89101995000500004"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870060206"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-014-7343-6"},{"key":"e_1_2_9_7_1","first-page":"143","article-title":"Brazilian\u2010Portuguese version of the SF\u201036. 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