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To obtain population\u2010average estimates, a Markov multistate model with theory\u2010based inverse probability weights was used to compute both the proportion of patients on sickness absence and the total sickness absence duration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>IDT patients were more likely than controls to receive sickness absence benefits at any given time (baseline: 49% vs. 46%; 5\u2010year follow\u2010up: 36% vs. 35%), and thereby also had a higher total duration, with a mean (95% CI) of 67 (87, 48) more days than controls over the 5\u2010year period. Intriguingly, sick leave was higher in IDT patients (563 [552, 573] vs. 478 [466, 490] days), whereas disability pension was higher in controls (152 [144, 160] vs. 169 [161, 178] days).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although sickness absence decreased over the study period in both IDT patients and controls, we found no support for IDT decreasing sickness absence more than other\/no interventions in chronic pain patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>In this large study of chronic pain patients in specialist healthcare, sickness absence is compared over a 5\u2010year period between patients in an interdisciplinary treatment programme and other\/no interventions. 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