{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:56:52Z","timestamp":1792177012607,"version":"4.4.0"},"reference-count":87,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T00:00:00Z","timestamp":1644192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The early identification of factors that increase risk of poor recovery from acute low back pain (LBP) is critical to prevent the transition to chronicity. Although most studies of risk factors for poor outcome in LBP tend to investigate the condition once it is already persistent, there is evidence to suggest that this differs from risk factors measured during the early\u2010acute stage. This study aimed to identify early risk factors for poor outcome in the short\u2010 and long\u2010term in individuals with acute LBP, and to compare this with factors identified at 3\u00a0months in the same cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred and thirty\u2010three individuals were recruited within 2\u00a0weeks of an acute LBP episode and completed questionnaires related to their sociodemographic, psychological, clinical and history\/treatment status at baseline and 3\u00a0months later, and their pain\u2010level fortnightly for 12\u00a0months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of the 133 participants recruited, follow\u2010up data were provided by 120 at 3\u00a0months, 97 at 6\u00a0months, 85 at 9\u00a0months and 94 at 12\u00a0months. Linear regression identified various factors at baseline (acute phase) and 3\u00a0months later that predicted short\u2010 and long\u2010term outcome (pain level, change in pain). Key findings were that: (1) depressive symptoms at baseline most consistently predicted worse outcome; (2) psychological factors in general at 3\u00a0months were more predictive of outcome than when measured at baseline; (3) early health care utilization predicted better outcome, whereas use of pain medication later (3\u00a0months) predicted worse outcome; and (4) sex and BMI predicted outcome inconsistently over 12\u2010months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results highlight the multidimensional nature of risk factors for poor outcome in LBP and the need to consider time variation in these factors.<\/jats:p>\n                    <jats:sec>\n                      <jats:title>Significance<\/jats:title>\n                      <jats:p>\n                        This study attempts to consider the impact of time variation of candidate risk factors on long\u2010term outcome from the very early onset of acute low back pain. Risk factors across domains (sociodemographic, psychological, clinical, history\/treatment) were identified, but their relationship with outcome often depended on when (acute phase\n                        <jats:italic>vs<\/jats:italic>\n                        . 3\u00a0months later) they were measured after back pain onset. Findings highlight the need to consider both a diverse range of factors and their potential time variance when assessing risk of poor outcome.\n                      <\/jats:p>\n                    <\/jats:sec>\n                  <\/jats:sec>","DOI":"10.1002\/ejp.1911","type":"journal-article","created":{"date-parts":[[2022,1,28]],"date-time":"2022-01-28T13:21:35Z","timestamp":1643376095000},"page":"835-854","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Risk factors for low back pain outcome: Does it matter when they are measured?"],"prefix":"10.1002","volume":"26","author":[{"given":"David Murray","family":"Klyne","sequence":"first","affiliation":[{"name":"NHMRC Centre of Clinical Research Excellence in Spinal Pain, Injury and Health School of Health and Rehabilitation Sciences The University of Queensland  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanne 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