{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:48:33Z","timestamp":1792176513722,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T00:00:00Z","timestamp":1675036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The primary aim of this observational study was to determine the incidence of trigeminal neuralgia (TN) in a county in central Sweden. The secondary aim was to investigate TN characteristics including the affected side and nerve branches.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients that received the ICD\u201010 diagnostic codes TN (G50.0), atypical facial pain (G50.1) and other\/unspecified disorder of the trigeminal nerve (G50.8 and G50.9) in Uppsala County, between 2009 and 2017, were eligible for inclusion. Case ascertainment was conducted by the authors by review of the medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The incidence of TN was estimated to be 5.5 (95% confidence interval 4.7\u20136.4) per 100,000 person\u2010years. The incidence increased with age, from 0.1 in 0\u2010 to 19\u2010year\u2010olds to 23.1 per 100,000 person\u2010years in 80+\u2010year\u2010olds. Females exhibited a higher incidence at 7.3 than males at 3.7 per 100,000 person\u2010years. Most of the trigeminal neuralgia cases were diagnosed in the Neurology department (47%). Trigeminal neuralgia was most frequently right sided (59%) and limited to one cranial nerve V\u2010branch, of which V2 was the most common.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Trigeminal neuralgia incidence was estimated to be 5.5 per 100,000 person\u2010years. The incidence was higher for females and increased with older age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>There is limited knowledge about the true incidence of trigeminal neuralgia. This manuscript provides an estimate of 5.5 cases per 100,000 person\u2010years, by using a thorough case ascertainment methodology.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.2081","type":"journal-article","created":{"date-parts":[[2023,1,21]],"date-time":"2023-01-21T07:48:48Z","timestamp":1674287328000},"page":"580-587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["Incidence of trigeminal neuralgia: A population\u2010based study in Central Sweden"],"prefix":"10.1002","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4556-5721","authenticated-orcid":false,"given":"Teodor","family":"Svedung\u00a0Wettervik","sequence":"first","affiliation":[{"name":"Department of Medical Sciences, Section of Neurosurgery Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Snel","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Section of Neurosurgery Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Kristiansson","sequence":"additional","affiliation":[{"name":"Department of Public Health and Caring Sciences, Section of Family Medicine and Preventive Medicine Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Ericson","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Section of Neurosurgery Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sami","family":"Abu\u00a0Hamdeh","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Section of Neurosurgery Uppsala University  Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2020.03.002"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(20)30233-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.12.026"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1914484"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102420949206"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.03.002"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001649"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/1744806920901890"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2296-9-26"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2006.01.030"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.3171\/2018.9.JNS181768"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102415611405"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0333102413485658"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198010000-00010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270114"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1159\/000110284"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.11.JNS141741"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2009.08.023"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.3344\/kjp.2021.34.3.332"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12384"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/head.12441"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.4.665"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-019-03981-7"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2011.10.003"},{"key":"e_1_2_8_26_1","unstructured":"SCB. (2017).Folkm\u00e4ngd i riket County och kommuner 31 December. och befolkningsf\u00f6r\u00e4ndringar 2017."},{"key":"e_1_2_8_27_1","unstructured":"SLF. (2022).https:\/\/slf.se\/var\u2010politik\/primarvard\/"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2020.106397"},{"key":"e_1_2_8_29_1","article-title":"Cerebrospinal fluid in classical trigeminal neuralgia: An exploratory study on candidate biomarkers","volume":"10","author":"Svedung Wettervik T.","year":"2022","journal-title":"Biomedicine"},{"key":"e_1_2_8_30_1","first-page":"89","volume-title":"Clinical anatomy","author":"Thomas K. L.","year":"2014"},{"key":"e_1_2_8_31_1","unstructured":"Uppsala R. (2019).https:\/\/www.regionuppsala.se\/sv\/Extranat\/For_vardgivare\/MOT\u2010PATIENTEN\/Sjukvard1\/Huslakarkansliet1\/Kapiteringslistor\/"}],"container-title":["European Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejp.2081","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ejp.2081","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejp.2081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T22:12:12Z","timestamp":1692569532000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ejp.2081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,30]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1002\/ejp.2081"],"URL":"https:\/\/doi.org\/10.1002\/ejp.2081","archive":["Portico"],"relation":{},"ISSN":["1090-3801","1532-2149"],"issn-type":[{"value":"1090-3801","type":"print"},{"value":"1532-2149","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,30]]},"assertion":[{"value":"2022-10-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}