{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T20:15:43Z","timestamp":1771877743967,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T00:00:00Z","timestamp":1700006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Chronic post\u2010surgical pain (CPSP) represents a significant issue for many patients following surgery; however, the long\u2010term incidence and impact have not been well described following cardiac surgery. Our aim was to characterize CPSP at least 5\u2009years following coronary artery bypass grafting (CABG) surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective observational study investigated a cohort of patients from a larger trial investigating cognitive outcomes following CABG surgery, with 89 of 148 eligible patients (60.1%) assessed for CPSP at a mean (standard deviation [SD]) of 6.8 [1.2] years. Questionnaires interrogated pain presence, intensity, location, neuropathic characteristics, Geriatric Depression Scale scores (GDS) and instrumental activities of daily living (IADL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>CPSP was described in 21\/89 (23.6%), with 10 rating it as moderate to severe. Six of the CPSP patients (29%) met criteria for neuropathic pain (6.7% overall). The highest rate of CPSP was associated with the leg surgical site (chest 12\/89 [13.5%], arm 8\/68 [11.8%] and leg (saphenous vein graft\u2014SVG) 11\/37 [29.7%]; <jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20096.523, <jats:italic>p\u2009=<\/jats:italic>\u20090.038). IADL scores were significantly lower for patients with CPSP (mean [SD]: 36.7 [1.6] vs. no CPSP 40.6 [0.6]; <jats:italic>p<\/jats:italic>\u2009=\u20090.006). Patients had GDS scores consistent with moderate depression (GDS &gt;8) in 3\/21 (14.3%) with CPSP, versus 3\/68 (4.4%) non\u2010CPSP patients (<jats:italic>\u03c7<\/jats:italic><jats:sup>2<\/jats:sup>\u2009=\u20093.20, <jats:italic>p\u2009=<\/jats:italic>\u20090.073).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study identified a CPSP incidence of 23.6% at a mean of 6.8\u2009years after CABG surgery, with the highest pain proportion at SVG harvest sites. CPSP was associated with neuropathic pain symptoms and had a significant impact on IADLs. This emphasizes the need for long\u2010term follow\u2010up of CABG patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>This study highlights the impact of CPSP 7\u2009years following cardiac surgery and highlights the effect of surgical site, neuropathic pain and the importance of including pain assessment and management in the long\u2010term follow\u2010up of cardiac surgical patients. Strategies to address and prevent chronic pain following cardiac surgery should be further explored.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.2203","type":"journal-article","created":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T06:59:48Z","timestamp":1700117988000},"page":"599-607","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The long\u2010term incidence of chronic post\u2010surgical pain after coronary artery bypass surgery \u2013 A prospective observational study"],"prefix":"10.1002","volume":"28","author":[{"given":"E.","family":"Charlton","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Acute Pain Medicine St Vincent's Hospital Melbourne  Fitzroy Victoria Australia"},{"name":"Melbourne Medical School The University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. J.","family":"Atkins","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Acute Pain Medicine St Vincent's Hospital Melbourne  Fitzroy Victoria Australia"},{"name":"Department of Critical Care Melbourne Medical School, University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Anesthesiology Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Evered","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Acute Pain Medicine St Vincent's Hospital Melbourne  Fitzroy Victoria Australia"},{"name":"Department of Critical Care Melbourne Medical School, University of Melbourne  Melbourne Victoria Australia"},{"name":"Department of Anesthesiology Weill Cornell Medicine  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Silbert","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Acute Pain Medicine St Vincent's Hospital Melbourne  Fitzroy Victoria Australia"},{"name":"Department of Critical Care Melbourne Medical School, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6637-0029","authenticated-orcid":false,"given":"D. A.","family":"Scott","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Acute Pain Medicine St Vincent's Hospital Melbourne  Fitzroy Victoria Australia"},{"name":"Department of Critical Care Melbourne Medical School, University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,11,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.12.010"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0304\u20103959(03)00017\u20104"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/2058738419838383"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.131012"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181afde28"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012624.pub2"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0304\u20103959(00)00466\u20108"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001143"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399\u20106576.2009.02097.x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40256\u2010014\u20100083\u20102"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.918"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(19)30352\u20106"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000000997"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.1794"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-6576.2001.450803.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.09.20"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(06)68700\u2010X"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u20105415.1988.tb07171.x"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2018.05.053"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399\u20106576.2001.450804.x"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.03.023"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7152"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/204946370900300102"},{"key":"e_1_2_10_25_1","first-page":"21","volume-title":"Acute pain management: Scientific evidence","author":"Rocket M.","year":"2020"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31823ac046"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.wad.0000213878.47924.44"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1300\/J018v05n01_09"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200606000-00007"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ca.22168"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022\u20103956(82)90033\u20104"}],"container-title":["European Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejp.2203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T06:22:01Z","timestamp":1710742921000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ejp.2203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,15]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1002\/ejp.2203"],"URL":"https:\/\/doi.org\/10.1002\/ejp.2203","archive":["Portico"],"relation":{},"ISSN":["1090-3801","1532-2149"],"issn-type":[{"value":"1090-3801","type":"print"},{"value":"1532-2149","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,15]]},"assertion":[{"value":"2023-05-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}