{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T12:24:03Z","timestamp":1753273443659,"version":"3.40.5"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Radiating leg pain is common in patients with low back pain (LBP). In this study, we aimed to determine the prevalence and incidence of LBP with radiating leg pain in Dutch general practice, and to describe the prescribed medications and requested imaging diagnostics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Rijnmond Primary Care Database containing over 500,000 primary care patients was used to select patients \u226518\u2009years with LBP with radiating leg pain between 2013 and 2021. Data on patient characteristics, LBP episodes, prescribed medication and requested imaging in the first 3\u2009months of an episode was extracted. Descriptive statistics were used to present patient characteristics and diagnostic\/therapeutic interventions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 27,695 patients were included. The total number of LBP with radiating leg pain episodes in these patients was 36,268. In 2021, the incidence and prevalence were 19.1 and 25.7 per 1000 patient years, respectively. In 60% of patients, the episode duration was shorter than 1\u2009month. In 62% of the episodes, patients visited the general practitioner (GP) one to two times. In 59% of the episodes, at least one medication was prescribed, non\u2010steroidal anti\u2010inflammatory drugs (NSAIDs) being the most common one (45%). In approximately 11% of the episodes, additional diagnostic imaging was requested.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>LBP with radiating leg pain is common in Dutch general practice patients. About 2\/3rd were prescribed pain medications. Dutch request few to none diagnostic imaging for these patients which is in line with clinical practice guidelines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>In this new study, we have gained insights into the incidence and prevalence of LBP with radiating leg pain in Dutch general practice. Both remained fairly stable over the study period of 9\u2009years (2013\u20132021). Overall, the care burden regarding seeking contact with the GPs and the requested diagnostics seem not to be that high. In 62% of the care episodes, there were one or two consultations with the GP, and in 11% of the episodes a diagnostic imaging was requested. Pain medications frequently prescribed (i.e. 2\/3rd of the episodes), with NSAIDs being the most common ones.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.2269","type":"journal-article","created":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T12:40:30Z","timestamp":1712234430000},"page":"1378-1386","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The prevalence, incidence and management of low back pain with radiating leg pain in Dutch general practice: A population\u2010based cohort study in the Rijnmond Primary Care Database"],"prefix":"10.1002","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8463-6257","authenticated-orcid":false,"given":"Ahmad Khoshal","family":"Khorami","sequence":"first","affiliation":[{"name":"Department of General Practice Erasmus MC, University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Chiarotto","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC, University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evelien I. T.","family":"de Schepper","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC, University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J. E.","family":"Bindels","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC, University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bart W.","family":"Koes","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC, University Medical Center Rotterdam  Rotterdam The Netherlands"},{"name":"Research Unit of General practice Departement of Public Health University of Southern Denmark  Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacoline J.","family":"van den Driest","sequence":"additional","affiliation":[{"name":"Department of General Practice Erasmus MC, University Medical Center Rotterdam  Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,4,4]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_9_2_1","DOI":"10.1007\/s00296-019-04430-5"},{"doi-asserted-by":"publisher","key":"e_1_2_9_3_1","DOI":"10.1097\/00007632-199503150-00014"},{"doi-asserted-by":"publisher","key":"e_1_2_9_4_1","DOI":"10.1097\/00007632-199612150-00023"},{"doi-asserted-by":"publisher","key":"e_1_2_9_5_1","DOI":"10.1093\/ije\/dyac026"},{"unstructured":"Devill\u00e9 W. &Wiegers T. A.(2012).Herijking stedelijke achterstandsgebieden (NIVEL).","key":"e_1_2_9_6_1"},{"doi-asserted-by":"publisher","key":"e_1_2_9_7_1","DOI":"10.1097\/00007632-200201010-00022"},{"doi-asserted-by":"publisher","key":"e_1_2_9_8_1","DOI":"10.1016\/j.ijmedinf.2007.09.001"},{"doi-asserted-by":"publisher","key":"e_1_2_9_9_1","DOI":"10.1007\/s00586-014-3355-2"},{"doi-asserted-by":"publisher","key":"e_1_2_9_10_1","DOI":"10.1097\/BRS.0b013e31820712bb"},{"doi-asserted-by":"publisher","key":"e_1_2_9_11_1","DOI":"10.1002\/art.34347"},{"doi-asserted-by":"publisher","key":"e_1_2_9_12_1","DOI":"10.1093\/fampra\/cmh409"},{"doi-asserted-by":"publisher","key":"e_1_2_9_13_1","DOI":"10.3390\/jcm10112482"},{"unstructured":"Khorami A. 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(2020).Neuropathic pain in adults: pharmacological management in non\u2010specialist settings.","key":"e_1_2_9_19_1"},{"doi-asserted-by":"publisher","key":"e_1_2_9_20_1","DOI":"10.1097\/BRS.0000000000002092"},{"doi-asserted-by":"publisher","key":"e_1_2_9_21_1","DOI":"10.1080\/09638280110066280"},{"doi-asserted-by":"publisher","key":"e_1_2_9_22_1","DOI":"10.3109\/02813432.2015.1006462"},{"key":"e_1_2_9_23_1","first-page":"A9122","article-title":"[revised NHG practice guideline \u2018Lumbosacral radicular syndrome\u2019] Herziene NHG\u2010standaard Lumbosacraal radiculair syndroom","volume":"159","author":"Verburg A. 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