{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:11:48Z","timestamp":1788869508546,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T00:00:00Z","timestamp":1396483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Centre for Clinical Research (CKF),","award":["9465"],"award-info":[{"award-number":["9465"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2014,11]]},"abstract":"Abstract<\/jats:title>\n \n Background<\/jats:title>\n \n The chronic pain (\n CP<\/jats:styled-content>\n ) and chronic multi\u2010site pain (\n CMP<\/jats:styled-content>\n ) condition is a highly prevalent health problem. Several studies have reported a high (31\u201364%) prevalence of co\u2010morbid restless legs syndrome (\n RLS<\/jats:styled-content>\n ) in patients with fibromyalgia, one specifically defined form of chronic widespread pain. The current study explored the association between\n CMP<\/jats:styled-content>\n and\n RLS<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Method<\/jats:title>\n \n The study included 4040 respondents to a postal questionnaire sent to 10,000 women in the age range of 18\u201364 years and randomly selected from the general population. Complete questionnaire data on type (acute\/chronic), degree (mild to severe) and spreading (0\u20135 body zones) of pain, as well as\n RLS<\/jats:styled-content>\n symptoms (validated questionnaire), were obtained from 3060 subjects. Information on lifestyle, anthropometrics, co\u2010morbidities and medication was collected.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n RLS<\/jats:styled-content>\n prevalence increased from 9.6% in subjects with no report of pain to 23,9%, 26.4%, 39.2%, 44.9% and 54.8% in those reporting one, two, three, four and five pain areas, respectively (\n p<\/jats:italic>\n \u2009<\u20090.001). Further,\n RLS<\/jats:styled-content>\n prevalence increased from 9.6% (no pain) to 27.9%, 37.9% and 42.4% in subjects with mild, moderate and severe chronic pain (\n p<\/jats:italic>\n \u2009<\u20090.001). Multi\u2010site pain, pain localized in the leg, extended pain duration and co\u2010morbid psychiatric disorder were all independently associated with a\n RLS<\/jats:styled-content>\n diagnosis in a multiple regression analysis.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n The prevalence of\n RLS<\/jats:styled-content>\n increased progressively with pain severity and even more sharply with the degree of pain spreading in women recruited from the general population. Both acute and chronic pain was associated with\n RLS<\/jats:styled-content>\n \u2010related symptoms.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/ejp.504","type":"journal-article","created":{"date-parts":[[2014,4,3]],"date-time":"2014-04-03T08:13:26Z","timestamp":1396512806000},"page":"1402-1409","source":"Crossref","is-referenced-by-count":25,"title":["High prevalence of restless legs syndrome among women with multi\u2010site pain: A population\u2010based study in\n D<\/scp>\n alarna,\n S<\/scp>\n weden"],"prefix":"10.1002","volume":"18","author":[{"given":"R.","family":"Stehlik","sequence":"first","affiliation":[{"name":"Pain Center Skonvik Medical Rehabilitation Clinic S\u00e4ter Sweden"},{"name":"Center for Sleep and Vigilance Disorders Sahlgrenska Academy Gothenburg University Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ulfberg","sequence":"additional","affiliation":[{"name":"Sleep Disorders Center Capio Lakargruppen Orebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Hedner","sequence":"additional","affiliation":[{"name":"Center for Sleep and Vigilance Disorders Sahlgrenska Academy Gothenburg University Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Grote","sequence":"additional","affiliation":[{"name":"Center for Sleep and Vigilance Disorders Sahlgrenska Academy Gothenburg University Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(03)00010-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(99)00298-2"},{"key":"e_1_2_8_4_1","first-page":"356","volume-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2000"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3109\/09638280902874154"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10253890310001650268"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2007.02.011"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1532-2149.2012.00130.x"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.57.7.1304"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/38.11.1035"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2009.00732.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2008.01.003"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(99)00308-5"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21191"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-200409000-00005"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(86)90327-9"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(02)00025-3"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.2174\/157015909790031201"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/ejcn.2009.149"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200203010-00017"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(83)90126-4"},{"key":"e_1_2_8_22_1","first-page":"1615","article-title":"Fibromyalgia \u2013 are there different mechanisms in the processing of pain? 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