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Although this pattern of increased reactivity has been established for the somatosensory modality, its generalization to other sensory modalities remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Auditory evoked potentials were obtained using a paired\u2010stimuli paradigm from a sample of 52 <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> female patients and 55 healthy women matched for age and socio\u2010economic status. Sensory gating of the <jats:styled-content style=\"fixed-case\">P50<\/jats:styled-content> component, as indicated by <jats:styled-content style=\"fixed-case\">P50<\/jats:styled-content> suppression rates to the second identical stimuli, was analysed in relation to clinical indices of <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>, including algometry of tender points and a number of self\u2010reported questionnaires.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sensory gating mechanisms in <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> patients proved to be normal, robust and as efficient as those recorded in control subjects. There was no correlation between <jats:styled-content style=\"fixed-case\">P50<\/jats:styled-content> suppression rates and indices of clinical or experimental (threshold or tolerance) pain. In addition, <jats:styled-content style=\"fixed-case\">P50<\/jats:styled-content> sensory gating was not related to the other main symptoms of <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content>, including fatigue, sleep dysfunction or co\u2010morbid depression, nor to hypersensitivity to noise or headache.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results indicate that <jats:styled-content style=\"fixed-case\">FM<\/jats:styled-content> patients do not present significant deficits in early sensory gating when processing auditory stimuli, and therefore challenge the \u2018generalized hypersensitivity\u2019 hypothesis of FM.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.627","type":"journal-article","created":{"date-parts":[[2014,11,28]],"date-time":"2014-11-28T16:41:56Z","timestamp":1417192916000},"page":"576-584","source":"Crossref","is-referenced-by-count":13,"title":["Filtering out repetitive auditory stimuli in fibromyalgia: A study 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