{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:57:12Z","timestamp":1791381432386,"version":"4.3.3"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,28]],"date-time":"2025-03-28T00:00:00Z","timestamp":1743120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Large population\u2010based estimates of the prevalence of painful temporomandibular disorders (p\u2010TMD) utilising standardised screening tools are scarce and have not investigated the prevalence of overlapping primary headaches. We aimed to estimate the prevalence of p\u2010TMD in a large population of young adults (18 to 23\u2009years) and to estimate the co\u2010occurrence of p\u2010TMD and two primary headaches, migraine and tension\u2010type headache (TTH). The study also aimed to examine the extent of psychological (PHQ\u20104) and physical (PHQ\u201015) comorbidities and report prevalence across three gender categories (\n                      <jats:italic>women<\/jats:italic>\n                      ,\n                      <jats:italic>men<\/jats:italic>\n                      and\n                      <jats:italic>other<\/jats:italic>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Survey data from the Danish National Birth Cohort were collected (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200911,982), in a cross\u2010sectional observational design. A sensitivity analysis was conducted to address participation bias, revealing minimal impact on the estimates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The overall prevalence of p\u2010TMD was 26.4% with gender\u2010specific prevalence of\n                      <jats:italic>women:<\/jats:italic>\n                      31.5%,\n                      <jats:italic>other:<\/jats:italic>\n                      39.2% and\n                      <jats:italic>men:<\/jats:italic>\n                      16.8%. Among those with p\u2010TMD, 80.5% reported headaches at least once a month, and 13.8% over 15\u2009days monthly. For the p\u2010TMD individuals with a medical headache diagnosis, 31.9% experienced TTH and 10.9% migraine. The study also identified a higher proportion of moderate\/severe psychological distress and physical symptoms in the p\u2010TMD group compared to the non\u2010p\u2010TMD group. Logistic regression revealed a positive association between PHQ\u20104 and p\u2010TMD, modified by gender (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.016).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>High overall prevalence of p\u2010TMD and overlapping primary headaches was found in young adults. In addition, the study reports gender\u2010specific associations between p\u2010TMD, psychological distress and physical comorbidities indicating that this association is stronger for men than for women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance Statement<\/jats:title>\n                    <jats:p>This study found a higher\u2010than\u2010expected prevalence of painful temporomandibular disorders in young adults. It is based on a large population cohort and used standardised and validated screening tools. The study also reported common co\u2010occurrence of primary headaches and explored gender differences. The study raises awareness for a possibly underestimated health burden in young individuals, particularly among individuals experiencing psychological distress and multiple physical symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejp.70013","type":"journal-article","created":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T19:32:53Z","timestamp":1743363173000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Prevalence of Painful Temporomandibular Disorders and Overlapping Primary Headaches Among Young Adults"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5200-8763","authenticated-orcid":false,"given":"Cristina Rocha","family":"Exposto","sequence":"first","affiliation":[{"name":"Department of Dentistry and Oral Health, Section for Orofacial Pain and Jaw Function Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojdeh","family":"Mansoori","sequence":"additional","affiliation":[{"name":"Department of Dentistry and Oral Health, Section for Orofacial Pain and Jaw Function Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodil Hammer","family":"Bech","sequence":"additional","affiliation":[{"name":"Department of Public Health, Research Unit of Epidemiology Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lene","family":"Baad\u2010Hansen","sequence":"additional","affiliation":[{"name":"Department of Dentistry and Oral Health, Section for Orofacial Pain and Jaw Function Aarhus University  Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468\u20102982.2008.01597.x"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.2009.01928.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002911"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1037\/sgd0000306"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016350903431118"},{"key":"e_1_2_8_7_1","first-page":"203","volume-title":"Epidemiology of Pain: A Report of the Task Force on Epidemiology of the International Association for the Study of Pain","author":"Drangsholt M.","year":"1999"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034516648088"},{"key":"e_1_2_8_9_1","first-page":"301","article-title":"Research Diagnostic Criteria for Temporomandibular Disorders: Review, Criteria, Examinations and Specifications, Critique","volume":"6","author":"Dworkin S. 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