{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T08:20:13Z","timestamp":1773476413491,"version":"3.50.1"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The rising volume of orthopaedic surgeries highlights the importance of optimal postoperative pain management, especially for trauma patients who frequently suffer inadequate analgesia and delayed recovery. This multicenter study aims to evaluate the prevalence of acute postoperative pain and identify contributing factors in traumatic and non\u2010traumatic orthopaedic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This multicenter study analysed adult orthopaedic surgery patients from the China Acute Postoperative Pain Study between September 2019 and August 2023. Patients with preoperative acute physical injuries requiring surgical intervention were defined as trauma patients. Using multivariate regression, we compared pain outcomes between trauma\/non\u2010trauma groups and identified risk factors for moderate\u2010to\u2010severe postoperative pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 10,892 orthopaedic patients (2833 trauma, 8059 non\u2010trauma), trauma patients showed higher rates of moderate\u2010to\u2010severe pain (57.3% vs. 50.1%), experienced more anxiety and helplessness, and had a greater desire for additional pain management than non\u2010trauma patients. Trauma was associated with the development of moderate\u2010to\u2010severe postoperative pain in both uni\u2010 and multivariate analyses (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Risk factors for postoperative pain differed: age over 65\u2009years and preoperative chronic pain were significant in non\u2010trauma patients, whereas intraoperative non\u2010opioid analgesics and local anaesthetic infiltration were associated with a decreased incidence of moderate\u2010to\u2010severe postoperative pain in trauma patients.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Over half of orthopaedic surgery patients experienced moderate to severe postoperative pain, with trauma patients reporting higher levels and greater impacts on their activities and emotional state, along with a greater need for additional pain relief. Distinct risk factors for trauma and non\u2010trauma patients highlight the need for personalised perioperative analgesic strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance Statement<\/jats:title>\n                    <jats:p>This study advances perioperative pain management by identifying trauma as an independent risk factor for moderate\u2010to\u2010severe postoperative pain in orthopaedic patients, with distinct risk profiles for trauma and non\u2010trauma subgroups. Trauma patients reported higher pain levels, greater distress and increased analgesic needs. These findings directly inform clinical practice, emphasising the need for personalised, risk\u2010stratified pain management to improve recovery. The results provide an evidence\u2010based framework for optimising analgesia in both trauma and elective orthopaedic surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejp.70147","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:43:10Z","timestamp":1760557390000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute Postoperative Pain in Orthopaedic Trauma and Non\u2010Trauma Patients: An Analysis of the China Acute Postoperative Pain Study (\n                    <scp>CAPOPS<\/scp>\n                    )"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6240-0371","authenticated-orcid":false,"given":"Lei","family":"Li","sequence":"first","affiliation":[{"name":"Department of Anesthesiology The First Medical Center of Chinese PLA General Hospital  Beijing 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