{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T14:45:46Z","timestamp":1792161946678,"version":"4.4.0"},"reference-count":45,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:00:00Z","timestamp":1792108800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The study objectives were to examine associations between participant\u2010reported alcohol consumption and (1) flares of low back pain (LBP) and (2) pain intensity at 1\u2010year follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This longitudinal case\u2010crossover study nested in a cohort included 474 participants with LBP who completed up to 36 scheduled assessments and additional patient\u2010initiated assessments (triggered by the onset of new flares) over a 1\u2010year period. Each assessment asked participants to report whether a LBP flare was present using a validated definition. Conditional logistic regression was used to estimate associations between alcohol consumption and subsequent flares. Linear regression was used to estimate associations between baseline alcohol consumption and LBP intensity at 1\u2010year follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In analyses of 10,251 assessments over 1\u2009year, each additional drink in the past 24\u2009h was associated with a slightly lower odds of subsequent LBP flares (odds ratio [OR] per drink 0.95, 95% CI: 0.90, 0.997). Each additional average number of drinks in the past 24\u2009h at baseline was significantly associated with slightly lower LBP intensity 1\u2009year later (\u22120.19 Numerical Rating Scale (NRS) points [95% CI: \u22120.38, \u22120.004]). However, this association was diminished and nonsignificant after adjusting for the number of drinks in the past 24\u2009h at the 1\u2010year follow\u2010up assessment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study suggests a small, transient protective association of alcohol with LBP flares in the immediate\u2010term, but no clinically meaningful beneficial associations with pain in the long\u2010term. The findings do not support alcohol use as a pain management strategy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Significance Statement<\/jats:title>\n                    <jats:p>This epidemiologic study did not find meaningful associations between alcohol consumption and low back pain intensity in the long\u2010term, although a small\u2010magnitude, transient association with lower risk of subsequent flares of low back pain was observed. These findings bridge gaps in the evidence between laboratory studies of acute analgesic effects of alcohol on pain perception and cohort studies examining long\u2010term low back pain outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejp.70424","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:58:01Z","timestamp":1792159081000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Alcohol Consumption and Associations With Short\u2010 and Long\u2010Term Outcomes in Low Back Pain: A Longitudinal Case\u2010Crossover Study"],"prefix":"10.1002","volume":"30","author":[{"given":"Adrienne D.","family":"Tanus","sequence":"first","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah F.","family":"Brubeck","sequence":"additional","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Timmons","sequence":"additional","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca I.","family":"Dowling","sequence":"additional","affiliation":[{"name":"University of South Florida  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janna L.","family":"Friedly","sequence":"additional","affiliation":[{"name":"University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Korpak","sequence":"additional","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clinton J.","family":"Daniels","sequence":"additional","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina A.","family":"Staab","sequence":"additional","affiliation":[{"name":"University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel K.","family":"Morelli","sequence":"additional","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Hodges","sequence":"additional","affiliation":[{"name":"University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalia","family":"Costa","sequence":"additional","affiliation":[{"name":"University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa A.","family":"Day","sequence":"additional","affiliation":[{"name":"University of Washington  Seattle Washington USA"},{"name":"University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Heagerty","sequence":"additional","affiliation":[{"name":"University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark P.","family":"Jensen","sequence":"additional","affiliation":[{"name":"University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9449-4165","authenticated-orcid":false,"given":"Pradeep","family":"Suri","sequence":"additional","affiliation":[{"name":"VA Puget Sound Health Care System  Seattle Washington USA"},{"name":"University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11606\u2010016\u20103586\u20105"},{"issue":"3","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1590\/S0102-36162008000200007","article-title":"Preval\u00eancia de dor Lombar Cr\u00f4nica na Popula\u00e7\u00e3o da Cidade de Salvador","volume":"43","author":"Almeida I. 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