{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:13:32Z","timestamp":1774260812522,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T00:00:00Z","timestamp":1432857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Quantitative sensory testing (<jats:styled-content style=\"fixed-case\">QST<\/jats:styled-content>) measures response to painful stimuli and has been used to predict post\u2010caesarean pain. Pain reported upon intravenous cannulation was shown to predict epidural analgesic use and pain intensity during labour. We hypothesized that pain intensity reported by women upon local anaesthesia injection (<jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content>) for spinal anaesthesia may predict acute pain after caesarean delivery (<jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In a prospective observational trial, 229 women undergoing elective <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content> under spinal anaesthesia were enrolled. Using standardized script before <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content>, women received <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content> (lidocaine 1% 2.5\u00a0mL via 25 G needle), and provided an <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content> score after the injection [verbal numeric pain scale (<jats:styled-content style=\"fixed-case\">VNPS<\/jats:styled-content>); 0\u2013100]. Demographic data, average, peak pain (at rest, with movement and uterine cramping) and analgesic requests were recorded for the first 24\u00a0h.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fourteen percent of women experienced severe pain (<jats:styled-content style=\"fixed-case\">VNPS<\/jats:styled-content> \u226570) upon <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content>. Good correlation was noted between <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content> and pain scores at rest and upon mobilization during the 24\u00a0h following surgery (average resting pain <jats:italic>r<\/jats:italic>\u00a0=\u00a00.529, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001, average pain at mobilization <jats:italic>r<\/jats:italic>\u00a0=\u00a00.483, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.0001). Severe acute postoperative pain (<jats:styled-content style=\"fixed-case\">VNPS<\/jats:styled-content> \u226570) was predicted by severe <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content> pain with a sensitivity of 91.6% and specificity of 93.3%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first study evaluating a clinical measure to predict post\u2010caesarean pain. Our main findings were that 14% of women experience severe pain upon <jats:styled-content style=\"fixed-case\">ILA<\/jats:styled-content>, which was associated with increased pain during the first 24\u00a0h.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.737","type":"journal-article","created":{"date-parts":[[2015,5,29]],"date-time":"2015-05-29T17:14:46Z","timestamp":1432919686000},"page":"1382-1388","source":"Crossref","is-referenced-by-count":27,"title":["Severe pain during local infiltration for spinal anaesthesia predicts post\u2010caesarean pain"],"prefix":"10.1002","volume":"19","author":[{"given":"S.","family":"Orbach\u2010Zinger","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Rabin Medical Center Beilinson Hospital Petach Tikvah Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Aviram","sequence":"additional","affiliation":[{"name":"Department of Obstetrics Gynecology Rabin Medical Center Beilinson Hospital Petach Tikvah 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