{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T08:06:09Z","timestamp":1790409969474,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,29]],"date-time":"2016-11-29T00:00:00Z","timestamp":1480377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Pain"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>This systematic review aimed at evaluating the efficacy, acceptability and safety of guided imagery\/hypnosis (<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>\/H) in fibromyalgia.\nCochrane Library, <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>, Psyc<jats:styled-content style=\"fixed-case\">INFO<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SCOPUS<\/jats:styled-content> were screened through February 2016. Randomized controlled trials (<jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s) comparing <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>\/H with controls were analysed. Primary outcomes were \u226550% pain relief, \u226520% improvement of health\u2010related quality of life, psychological distress, disability, acceptability and safety at end of therapy and 3\u2010month follow\u2010up. Effects were summarized by a random effects model using risk differences (<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content>) or standardized mean differences (<jats:styled-content style=\"fixed-case\">SMD<\/jats:styled-content>) with 95% confidence intervals (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>).Seven <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s with 387 subjects were included into a comparison of <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>\/H versus controls. There was a clinically relevant benefit\u00a0of <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>\/H compared to controls on \u226550% pain relief [<jats:styled-content style=\"fixed-case\">RD<\/jats:styled-content> 0.18 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.02, 0.35)] and psychological distress [<jats:styled-content style=\"fixed-case\">SMD<\/jats:styled-content> \u22120.40 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u22120.70, \u22120.11)] at the end of therapy. Acceptability at the end of treatment for <jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>\/H was not significantly different to the control. Two <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content>s with 95 subjects were included in the comparison of hypnosis combined with cognitive behavioural therapy (<jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content>) versus <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content> alone. Combined therapy was superior to <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content> alone in reducing psychological distress at the end of therapy [<jats:styled-content style=\"fixed-case\">SMD<\/jats:styled-content> \u22120.50 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> \u22120.91, \u22120.09)]. There were no statistically significant differences between combined therapy and <jats:styled-content style=\"fixed-case\">CBT<\/jats:styled-content> alone in other primary outcomes at the end of treatment and follow\u2010up. No study reported on safety.\n<jats:styled-content style=\"fixed-case\">GI<\/jats:styled-content>\/H hold promise in a multicomponent management of fibromyalgia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Significance<\/jats:title><jats:p>We provide a systematic review with meta\u2010analysis on guided imagery and hypnosis for fibromyalgia. Current analyses endorse the efficacy and tolerability of guided imagery\/hypnosis and of the combination of hypnosis with cognitive\u2013behavioural therapy in reducing key symptoms of fibromyalgia.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejp.933","type":"journal-article","created":{"date-parts":[[2016,11,29]],"date-time":"2016-11-29T08:22:42Z","timestamp":1480407762000},"page":"217-227","source":"Crossref","is-referenced-by-count":104,"title":["Efficacy, acceptability and safety of guided imagery\/hypnosis in fibromyalgia \u2013 A systematic review and meta\u2010analysis of randomized controlled trials"],"prefix":"10.1002","volume":"21","author":[{"given":"N.","family":"Zech","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology Universit\u00e4tsklinikum Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Hansen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Universit\u00e4tsklinikum 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