{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T14:58:21Z","timestamp":1747148301292,"version":"3.40.5"},"reference-count":57,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T00:00:00Z","timestamp":1714780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100014607","name":"Royal Children's Hospital Foundation","doi-asserted-by":"publisher","award":["2014\u2010241"],"award-info":[{"award-number":["2014\u2010241"]}],"id":[{"id":"10.13039\/100014607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020013","name":"NIHR Leicester Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020013","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","award":["100660"],"award-info":[{"award-number":["100660"]}],"id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005381","name":"Financial Markets Foundation for Children","doi-asserted-by":"publisher","award":["2014\u2010055","2016\u2010310"],"award-info":[{"award-number":["2014\u2010055","2016\u2010310"]}],"id":[{"id":"10.13039\/501100005381","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014555","name":"Murdoch Children's Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100014555","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Physical activity (PA) during childhood and adolescence is important for the accrual of maximal peak bone mass. The precise dose that benefits bone remains unclear as methods commonly used to analyze PA data are unsuitable for measuring bone\u2010relevant PA. Using improved accelerometry methods, this study identified the amount and intensity of PA most strongly associated with bone outcomes in 11\u201312\u2010year\u2010olds. Participants (<jats:italic>n<\/jats:italic>\u00a0=\u00a0770; 382 boys) underwent tibial peripheral quantitative computed tomography to assess trabecular and cortical density, endosteal and periosteal circumference and polar stress\u2010strain index. Seven\u2010day wrist\u2010worn raw acceleration data averaged over 1\u2010s epochs was used to estimate time accumulated above incremental PA intensities (50 milli\u2010gravitational unit (m<jats:italic>g<\/jats:italic>) increments from 200 to 3000\u00a0m<jats:italic>g<\/jats:italic>). Associations between time spent above each 50\u00a0m<jats:italic>g<\/jats:italic> increment and bone outcomes were assessed using multiple linear regression, adjusted for age, sex, height, weight, maturity, socioeconomic position, muscle cross\u2010sectional area and PA below the intensity of interest. There was a gradual increase in mean <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> change across all bone\u2010related outcomes as the intensity increased in 50\u00a0m<jats:italic>g<\/jats:italic> increments from &gt;200 to &gt;700\u00a0m<jats:italic>g<\/jats:italic>. All outcomes became significant at &gt;700\u00a0m<jats:italic>g<\/jats:italic> (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> change\u00a0=\u00a00.6%\u20131.3% and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.001\u20130.02). Any further increases in intensity led to a reduction in mean <jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> change and associations became non\u2010significant for all outcomes &gt;1500\u00a0m<jats:italic>g<\/jats:italic>. Using more appropriate accelerometry methods (1\u2010s epochs; no a priori application of traditional cut\u2010points) enabled us to identify that \u223c10\u00a0min\/day of PA &gt;700\u00a0m<jats:italic>g<\/jats:italic> (equivalent to running \u223c10\u00a0km\/h) was positively associated with pQCT\u2010derived measures of bone density, geometry and strength in 11\u201312\u2010year\u2010olds.<\/jats:p>","DOI":"10.1002\/ejsc.12122","type":"journal-article","created":{"date-parts":[[2024,5,4]],"date-time":"2024-05-04T12:24:18Z","timestamp":1714825458000},"page":"987-998","source":"Crossref","is-referenced-by-count":0,"title":["Improving the identification of bone\u2010specific physical activity using wrist\u2010worn accelerometry: A cross\u2010sectional study in 11\u201312\u2010year\u2010old Australian children"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7987-5616","authenticated-orcid":false,"given":"Gemma","family":"Brailey","sequence":"first","affiliation":[{"name":"Department of Public Health and Sport Sciences Faculty of Health and Life Sciences University of Exeter  Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad","family":"Metcalf","sequence":"additional","affiliation":[{"name":"Department of Public Health and Sport Sciences Faculty of Health and Life Sciences University of Exeter  Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Price","sequence":"additional","affiliation":[{"name":"Department of Public Health and Sport Sciences Faculty of Health and Life Sciences University of Exeter  Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean","family":"Cumming","sequence":"additional","affiliation":[{"name":"Department for Health University of Bath  Bath UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Rowlands","sequence":"additional","affiliation":[{"name":"Diabetes Research Centre Leicester General Hospital University of Leicester  Leicester UK"},{"name":"National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC) University Hospitals of Leicester NHS Trust and the University of Leicester  Leicester UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy","family":"Olds","sequence":"additional","affiliation":[{"name":"Alliance for Research in Exercise, Nutrition, and Activity University of South Australia  Adelaide South Australia Australia"},{"name":"Murdoch Children's Research Institute Royal Children's Hospital  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Simm","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute Royal Children's Hospital  Parkville Victoria Australia"},{"name":"Department of Endocrinology and Diabetes Royal Children's Hospital  Parkville Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Wake","sequence":"additional","affiliation":[{"name":"Murdoch Children's Research Institute Royal Children's Hospital  Parkville Victoria Australia"},{"name":"Department of Paediatrics University of Melbourne  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Stiles","sequence":"additional","affiliation":[{"name":"Department of Public Health and Sport Sciences Faculty of Health and Life Sciences University of Exeter  Exeter UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,5,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2019.1693320"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1999.14.10.1672"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768\u2010199507000\u201000012"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2006.10.004"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.412"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2036"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/17518423.2012.762590"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223\u2010013\u20109803\u2010x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/s0036\u201036342009000700004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2011.03.013"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-022-06362-6"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2015.04.005"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.2307\/1130220"},{"volume-title":"Longitudinal Study of Australian Children's Child Health Checkpoint Data User Guide","year":"2018","author":"Clifford S.","key":"e_1_2_8_15_1"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102017\u2010020261"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12966\u2010015\u20100274\u20105"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyu203"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2017.12.028"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.1631"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4143"},{"key":"e_1_2_8_22_1","first-page":"5","article-title":"Growing up in Australia: The Longitudinal Study of Australian Children: Entering Adolescence and Becoming a Young Adult","author":"Edwards B","year":"2014","journal-title":"Family Matters"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000000771"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.414"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102018\u2010023194"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.mss.0000185658.28284.ba"},{"key":"e_1_2_8_27_1","first-page":"4","article-title":"Growing Up in Australia: The Longitudinal Study of Australian Children","author":"Gray M.","year":"2005","journal-title":"Family Matters"},{"key":"e_1_2_8_28_1","first-page":"514","article-title":"Accelerometer\u2010Based Osteogenic Indices, Moderate\u2010To\u2010Vigorous and Vigorous Physical Activity, and Bone Traits in Adolescents","volume":"22","author":"Haapala E. A.","year":"2022","journal-title":"Journal of Musculoskeletal and Neuronal Interactions"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000000289"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198\u2010006\u20100172\u20104"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198\u2010010\u20101333\u2010z"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01055.2002"},{"volume-title":"International Standards for Anthropometric Assessment","year":"2006","author":"Marfell\u2010Jones M.","key":"e_1_2_8_35_1"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1123\/jmpb.2018\u20100063"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocd.2007.11.002"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1123\/pes.14.1.87"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2018.04.011"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf01622201"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf01537962"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2012.05.013"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2012.709266"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1123\/pes.2018\u20100201"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000002047"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000001435"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000000978"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2012.03.005"},{"key":"e_1_2_8_49_1","unstructured":"Statistics ABo.2011.Census of Population and Housing: Socio\u2010Economic Indexes for Areas (SEIFA).Australian Bureau of Statistics.https:\/\/www.abs.gov.au\/websitedbs\/censushome.nsf\/home\/seifa2011"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyx080"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000001704"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12966\u2010020\u201000929\u20104"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003677\u2010200301000\u201000009"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00421.2014"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061691"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102018\u2010022400"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198\u2010015\u20103440\u20103"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.mss.0000185660.38335.de"}],"container-title":["European Journal of Sport Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejsc.12122","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T04:26:47Z","timestamp":1719980807000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ejsc.12122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,4]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/ejsc.12122"],"URL":"https:\/\/doi.org\/10.1002\/ejsc.12122","archive":["Portico"],"relation":{},"ISSN":["1746-1391","1536-7290"],"issn-type":[{"type":"print","value":"1746-1391"},{"type":"electronic","value":"1536-7290"}],"subject":[],"published":{"date-parts":[[2024,5,4]]}}}