{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T06:40:04Z","timestamp":1756017604361,"version":"3.44.0"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T00:00:00Z","timestamp":1745280000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The aim of this study was to assess the effects of oxygen availability (normoxia vs. hypoxia), muscle mass and exercise type on pulse oxygen saturation, and quadriceps muscle oxygenation during repeated sprint exercises. Sixteen healthy participants completed 5  12 s sprints (21 s rest). This sprint\u2010like exercise was performed under two environmental conditions (normoxia: FiO<jats:sub>2<\/jats:sub>\u00a0=\u00a021%; systemic hypoxia: FiO<jats:sub>2<\/jats:sub>\u00a0=\u00a013%) and for three exercise modalities: unilateral knee extensions (KE) involving the right leg extensors (UNI), bilateral KE involving both legs extensors (BIL), and bilateral leg cycling (CYC). Measurements included power output, pulse oxygen saturation (SpO<jats:sub>2<\/jats:sub>), and <jats:italic>vastus lateralis<\/jats:italic> oxygenation (delta in tissue saturation index; \u0394TSI). In hypoxia, a similar minimal SpO<jats:sub>2<\/jats:sub> was reported in UNI and BIL but SpO<jats:sub>2<\/jats:sub> was lower in CYC (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.047 and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.021). \u0394TSI during sprints and recoveries were similar in UNI and BIL but greater in CYC (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) and in normoxia compared to hypoxia (main condition effect; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002). The power output was lower during KE exercises than during cycling, and no effect of hypoxia has been reported. The main results of this study indicate that unilateral and bilateral KE at high intensity induce comparable pulse and local muscular desaturation in hypoxia, and that these alterations are exacerbated during cycling.<\/jats:p>","DOI":"10.1002\/ejsc.12234","type":"journal-article","created":{"date-parts":[[2025,4,22]],"date-time":"2025-04-22T13:04:01Z","timestamp":1745327041000},"source":"Crossref","is-referenced-by-count":0,"title":["Muscle deoxygenation responses are similar between repeated sprints in hypoxia performed with uni\u2010 versus\u00a0bi\u2010lateral knee extensions but reduced compared to cycling"],"prefix":"10.1002","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9401-6080","authenticated-orcid":false,"given":"Lo\u00efs","family":"Mougin","sequence":"first","affiliation":[{"name":"Inter\u2010University Laboratory of Human Movement Sciences Savoie Mont\u2010Blanc University  Chamb\u00e9ry France"},{"name":"School of Sport Exercise and Health Sciences 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