{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T17:44:47Z","timestamp":1755798287705,"version":"3.44.0"},"reference-count":31,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T00:00:00Z","timestamp":1749859200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>Exogenous carbohydrate (CHO) supplementation during exercise is an efficient strategy to enhance endurance performance. However, the effects of low\u2010to\u2010moderate amounts of exogenous CHO on time to exhaustion (TTE) have not been fully investigated. Nineteen healthy moderately active participants (26.2\u00a0\u00b1\u00a01.7\u00a0years and BMI: 22.4\u00a0\u00b1\u00a02.3\u00a0kg\u00b7m<jats:sup>\u22122<\/jats:sup>) performed four TTE tests at the second lactate turn point (LTP2) in a double\u2010blind, randomised and placebo\u2010controlled setting consuming either 20, 40 and 60\u00a0g\u00b7L<jats:sup>\u22121<\/jats:sup>\u00b7h<jats:sup>\u22121<\/jats:sup> of a glucose and fructose combination (CHO<jats:sub>20,<\/jats:sub> CHO<jats:sub>40<\/jats:sub> and CHO<jats:sub>60<\/jats:sub>) or a placebo (PLA). Glucose [Glu<jats:sup>\u2212<\/jats:sup>] and lactate concentrations [La<jats:sup>\u2212<\/jats:sup>] as well as ventilatory, heart rate (HR) and rating of perceived exertion (RPE) values were recorded during the tests. There were no statistically significant differences in TTE (PLA: 32.5\u00a0\u00b1\u00a09.6\u00a0min, CHO<jats:sub>20<\/jats:sub>: 35.9\u00a0\u00b1\u00a014.5\u00a0min, CHO<jats:sub>40<\/jats:sub>: 35.1\u00a0\u00b1\u00a012.9\u00a0min, CHO<jats:sub>60<\/jats:sub>: 38.0\u00a0\u00b1\u00a017.5\u00a0min and <jats:italic>p<\/jats:italic>\u00a0=\u00a00.11). Within each trial arm, no statistically significant differences were found between pre\u2010 and post\u2010exercise [Glu<jats:sup>\u2212<\/jats:sup>] (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a00.05). Post\u2010exercise [Glu<jats:sup>\u2212<\/jats:sup>] for CHO<jats:sub>60<\/jats:sub> were significantly higher when compared to PLA (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.03). Lastly, mean ventilatory parameters as well as HR and RPE during exercise showed no statistically significant differences between trial arms (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a00.05). Low\u2010to\u2010moderate amounts of exogenous CHO do not increase TTE in healthy moderately active individuals when compared to a placebo. Therefore, when exercising for less than 60\u00a0min at high intensities, exogenous CHO supplementation is not necessary if a CHO rich diet is followed prior to exercise.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trial Registration<\/jats:title><jats:p>DRKS\u2010ID: DRKS00030531<\/jats:p><\/jats:sec>","DOI":"10.1002\/ejsc.12326","type":"journal-article","created":{"date-parts":[[2025,6,14]],"date-time":"2025-06-14T11:58:44Z","timestamp":1749902324000},"source":"Crossref","is-referenced-by-count":0,"title":["Effect of Low\u2010To\u2010Moderate Exogenous Carbohydrate Supplementation on Time to Exhaustion During Constant Load Intense Cycling in Healthy Individuals. 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