{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T16:14:33Z","timestamp":1789834473075,"version":"4.0.1"},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T00:00:00Z","timestamp":1773100800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Breast cancer treatment impairs aerobic and neuromuscular capacities, leading to a decrease in quality of life. Exercise may counteract these effects if it is individualized to patient characteristics. This study aimed to assess the feasibility and potential effects of combined concentric and eccentric cycling training on exercise capacity. Twenty\u2010one patients with breast cancer (59\u00a0\u00b1\u00a09\u00a0years; 164\u00a0\u00b1\u00a05\u00a0cm; and 72\u00a0\u00b1\u00a013\u00a0kg) were assessed before and after exercise training twice a week for six weeks. Assessments included a test to determine power output at ventilatory threshold (P\n                    <jats:sub>VT<\/jats:sub>\n                    ), a 6\u2010min walking test (6\u2010MWT), and a measure of quadriceps muscle force and architecture. Exercise training adherence, attendance and rate of perceived exertion (RPE) were also measured. The exercise training included two concentric cycling bouts (7\u00a0\u00d7\u00a01\u00a0min at 130%P\n                    <jats:sub>VT<\/jats:sub>\n                    and 5\u00a0\u00d7\u00a02\u00a0min at 110%P\n                    <jats:sub>VT<\/jats:sub>\n                    ) and one eccentric cycling bout (7\u00a0\u00d7\u00a01\u00a0min at 130%P\n                    <jats:sub>VT<\/jats:sub>\n                    ). The exercise training protocol was associated with high attendance (90%) and adherence (98%) rates and was well tolerated (3.5\/10 of RPE). From pre\u2010 to postexercise training, we documented an increase in aerobic capacity, characterized by increased oxygen consumption (+11.1% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.001) and power output (+10.9% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.004) at VT. These changes were accompanied by neuromuscular adaptations, with greater muscle force (+18.3% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001),\n                    <jats:italic>vastus lateralis<\/jats:italic>\n                    thickness (+5.0% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.031), fascicle length (+11.9% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001), pennation angle (+11.3% and\n                    <jats:italic>p\u00a0=<\/jats:italic>\n                    \u00a00.001), and\n                    <jats:italic>rectus femoris<\/jats:italic>\n                    cross\u2010sectional area (+11.6% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.020). These adaptations led to increased 6\u2010MWT distance (+4.4% and\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.005). Thanks to an individualized exercise training with high adherence and attendance, aerobic and neuromuscular parameters were improved, leading to greater exercise capacity in breast cancer.\n                  <\/jats:p>","DOI":"10.1002\/ejsc.70153","type":"journal-article","created":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:27:54Z","timestamp":1773156474000},"source":"Crossref","is-referenced-by-count":1,"title":["Feasibility and Potential Effects of Exercise Training Combining Eccentric and Concentric Cycling in Patients With Breast Cancer"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9236-6514","authenticated-orcid":false,"given":"Elyse","family":"Hucteau","sequence":"first","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"},{"name":"Biomedicine Research Center of Strasbourg (CRBS) UR 3072 \u201cMitochondrie, Stress Oxydant et Plasticit\u00e9 Musculaire\u201d University of Strasbourg  Strasbourg France"},{"name":"Faculty of Sport Sciences European Center for Education Research and Innovation in Exercise Physiology (CEERIPE) University of Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J.","family":"Hureau","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"},{"name":"Biomedicine Research Center of Strasbourg (CRBS) UR 3072 \u201cMitochondrie, Stress Oxydant et Plasticit\u00e9 Musculaire\u201d University of Strasbourg  Strasbourg France"},{"name":"Faculty of Sport Sciences European Center for Education Research and Innovation in Exercise Physiology (CEERIPE) University of Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Decor","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9o","family":"Weltzer","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"},{"name":"Biomedicine Research Center of Strasbourg (CRBS) UR 3072 \u201cMitochondrie, Stress Oxydant et Plasticit\u00e9 Musculaire\u201d University of Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0185-9257","authenticated-orcid":false,"given":"Nabil","family":"Kouzkouz","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"},{"name":"Biomedicine Research Center of Strasbourg (CRBS) UR 3072 \u201cMitochondrie, Stress Oxydant et Plasticit\u00e9 Musculaire\u201d University of Strasbourg  Strasbourg France"},{"name":"Faculty of Sport Sciences European Center for Education Research and Innovation in Exercise Physiology (CEERIPE) University of Strasbourg  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Bischoff","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Somme","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roland","family":"Schott","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Pivot","sequence":"additional","affiliation":[{"name":"Exercise Physiology Laboratory Institut Strauss  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan 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