{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:45:51Z","timestamp":1782740751058,"version":"3.54.5"},"reference-count":65,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T00:00:00Z","timestamp":1775260800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["BA200299"],"award-info":[{"award-number":["BA200299"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This study aimed to determine whether fat metabolism differs between males and females when exposed to extreme exercise\u2010heat stress. Physically active males (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a011, 23\u00a0\u00b1\u00a04\u00a0years, 81.7\u00a0\u00b1\u00a011.8\u00a0kg, body fat 16.4\u00a0\u00b1\u00a06.6%) and females (\n                    <jats:italic>n<\/jats:italic>\n                    \u00a0=\u00a013, 25\u00a0\u00b1\u00a04\u00a0years, 60.4\u00a0\u00b1\u00a07.1\u00a0kg, 24.4\u00a0\u00b1\u00a06.7%) completed a 2\u2010h exercise\u2010heat tolerance test (40C, 40% relative humidity). Differences (pre\u2010, post\u2010, change, and mean difference (MD)) within and between groups were analyzed. The subcutaneous abdominal adipose tissue (SCAAT) interstitial glycerol concentration and adipose tissue blood flow (ethanol Output:Input (O:I)) pre\u2010exercise, every 30\u00a0min (min) of exercise, and during recovery was measured with microdialysis. Non\u2010esterified fatty acids, insulin, insulin\u2010like growth factor, epinephrine and norepinephrine, and cortisol were measured in blood. Resting energy expenditure (REE) was measured pre\u2010 and post\u2010exercise and exercising metabolic heat production (MHP) was collected during 30 and 90\u00a0min of the HTT. Despite no sex differences in systemic blood biomarkers, fat oxidation (\n                    <jats:italic>g<\/jats:italic>\n                    \u00a0\u00d7\u00a0min\n                    <jats:sup>\u22121<\/jats:sup>\n                    ) was higher in males (M) (vs. Females (F)) at 30\u00a0min of HTT (3.92\u00a0\u00b1\u00a00.25 (M), 3.58\u00a0\u00b1\u00a00.38 (F),\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.021). SCAAT interstitial glycerol was similar across all time points between sexes (baseline glycerol ranges (mmol\u00a0\u00d7\u00a0L\n                    <jats:sup>\u22121<\/jats:sup>\n                    ): 104.6\u20131260.0 (F), 165.0\u2013775.6 (M)); however, females had a greater O:I ratio at 90\u00a0min of exercise (vs. M) (0.69\u00a0\u00b1\u00a00.33 (F); 0.44\u00a0\u00b1\u00a00.20 (M);\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.033). Pre\u2010 and post\u2010exercise REE were 23% (MD: 447.5\u00a0kcal\u00a0\u00d7\u00a0day\n                    <jats:sup>\u22121<\/jats:sup>\n                    ,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001) and 25% (MD: 485\u00a0kcal\u00a0\u00d7\u00a0day\n                    <jats:sup>\u22121<\/jats:sup>\n                    ,\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001) lower in females compared to males. Post\u2010exercise RER (0.67\u00a0\u00b1\u00a00.06 (F); 0.72\u00a0\u00b1\u00a00.08 (M);\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.045) and mean MHP was higher in males (MD: 94W). Fat oxidation was higher in males compared to females at 30\u00a0min with no changes in SCAAT lipolysis or blood biomarkers before or after an acute bout of exercise\u2010heat stress.\n                  <\/jats:p>","DOI":"10.1002\/ejsc.70162","type":"journal-article","created":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:28:23Z","timestamp":1775302103000},"source":"Crossref","is-referenced-by-count":0,"title":["Fat Oxidation, But Not Subcutaneous Adipose Tissue Lipolysis, Differs Between Males and Females During a Treadmill\u2010Based Heat Tolerance Test"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4488-3648","authenticated-orcid":false,"given":"Margaret C.","family":"Morrissey\u2010Basler","sequence":"first","affiliation":[{"name":"Department of Kinesiology Korey Stringer Institute University of Connecticut  Storrs Connecticut USA"},{"name":"Department of Health Sciences Providence College  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Szymanski","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Korey Stringer Institute University of Connecticut  Storrs Connecticut USA"},{"name":"Department of Clinical and Applied Movement of Sciences University of Northern Florida  Jacksonville Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7746-8475","authenticated-orcid":false,"given":"Erica M.","family":"Filep","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Korey Stringer Institute University of Connecticut  Storrs Connecticut USA"},{"name":"School of Sport Science Endicott College  Beverly Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9598-6586","authenticated-orcid":false,"given":"Sean P.","family":"Langan","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Korey Stringer Institute University of Connecticut  Storrs Connecticut USA"},{"name":"VO Health, Inc.  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1939-7656","authenticated-orcid":false,"given":"Michael J.","family":"Ormsbee","sequence":"additional","affiliation":[{"name":"Department of Nutrition Food and Exercise Sciences Institute of Sports Sciences and Medicine Florida State University  Tallahassee Florida USA"},{"name":"Discipline of Biokinetics Exercise and Leisure Sciences School of Health Sciences University of KwaZulu\u2010Natal  Durban South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Korey Stringer Institute University of Connecticut  Storrs Connecticut USA"},{"name":"Department of Kinesiology University of Connecticut  Storrs Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas J.","family":"Casa","sequence":"additional","affiliation":[{"name":"Department of Kinesiology Korey Stringer Institute University of Connecticut  Storrs Connecticut USA"},{"name":"Department of Kinesiology University of Connecticut  Storrs Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,4]]},"reference":[{"key":"e_1_2_15_2_1","unstructured":"AbrahamssonP.2010. \u201cMethodological Aspects on Microdialysis Sampling and Measurements.\u201d59."},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/db11\u20100219"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00752.2018"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxz186"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e31802fa199"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.6.2514"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.20.2.145"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1017\/s0029665199001214"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci114516"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.2023\u20100150"},{"key":"e_1_2_15_12_1","article-title":"Fitting Linear Mixed\u2010Effects Models Using lme4","author":"Bates D.","year":"2014","journal-title":"arXiv"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0000000000001498"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0026\u20100495(00)80031\u20101"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010319\u201070178\u20103_2"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1079\/bjn2001471"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062\u20106050\u201050.9.07"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11892\u2010018\u20101031\u20103"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1208\/aapsj070369"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01312.2013"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00906.2015"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748\u20101716.1995.tb09850.x"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/s135772980005459x"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2013.200"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00527.2011"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2012.240739"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/bf02474537"},{"key":"e_1_2_15_28_1","doi-asserted-by":"crossref","unstructured":"GieringK. 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