{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T13:45:51Z","timestamp":1782740751054,"version":"3.54.5"},"reference-count":65,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    This randomized controlled trial examined the effects of a 10\u2010week high\u2010intensity interval training (HIIT) program on physiological and hematological outcomes in 28 adolescent girls with overweight or obesity. Participants were randomly assigned to a HIIT group or a control group. The HIIT protocol comprised 4 sets of 6 \u00d7 15\u2010s bouts at 90%\u2013105% of maximal aerobic speed (MAS), interspersed with 15\u2010s active recovery at 50% MAS, performed three times per week. Significant group\u00d7time interactions were observed for body composition, aerobic capacity, maximal heart rate (HRmax), erythrocytes, hemoglobin, hematocrit, creatine kinase (CK), and lactate dehydrogenase (LDH). Between\u2010group comparisons showed greater improvements in body mass, body fat, waist circumference, MAS, estimated VO\n                    <jats:sub>2<\/jats:sub>\n                    max, and plasma volume in the HIIT group compared with controls, though not all differences reached statistical significance. Within\u2010group analysis in the HIIT group revealed reductions in body mass (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.37), body fat (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.001,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.78), waist circumference (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.54), HRmax (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.020,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.88), erythrocytes (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.007,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.46), hemoglobin (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.019,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.84), hematocrit (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.004,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.34), CK (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.049,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.29), and LDH (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.032,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.41), alongside increases in MAS (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.007,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.64) and estimated VO\n                    <jats:sub>2<\/jats:sub>\n                    max (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0=\u00a00.007,\n                    <jats:italic>d<\/jats:italic>\n                    \u00a0=\u00a00.64). Plasma volume variation was also higher in the HIIT group. Overall, a 10\u2010week HIIT intervention enhanced body composition, plasma volume, and cardiorespiratory fitness, while reducing markers of muscular and metabolic stress. These results indicate that HIIT is a feasible and effective approach for improving physiological and metabolic health in adolescent girls with overweight or obesity, supporting its potential as a targeted exercise strategy in this population.\n                  <\/jats:p>","DOI":"10.1002\/ejsc.70181","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:20:01Z","timestamp":1777432801000},"source":"Crossref","is-referenced-by-count":0,"title":["Cardiorespiratory and Hematological Responses to High\u2010Intensity Interval Training in Adolescent Girls With Overweight or Obesity: A Randomized Controlled Trial"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6418-6711","authenticated-orcid":false,"given":"Wissal","family":"Abassi","sequence":"first","affiliation":[{"name":"Research Unit \u201cSport Sciences Health and Movement\u201d (UR22JS01) High Institute of Sport and Physical Education of Kef University of Jendouba  Kef Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8840-1735","authenticated-orcid":false,"given":"Nejmeddine","family":"Ouerghi","sequence":"additional","affiliation":[{"name":"Research Unit \u201cSport Sciences Health and Movement\u201d (UR22JS01) High Institute of Sport and Physical Education of Kef University of Jendouba  Kef Tunisia"},{"name":"Faculty of Medicine of Tunis University of Tunis el Manar Rabta Hospital  Tunis Tunisia"},{"name":"University of Gafsa High Institute of Sport and Physical Education of Gafsa  Gafsa Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1585-4052","authenticated-orcid":false,"given":"Moncef","family":"Feki","sequence":"additional","affiliation":[{"name":"Faculty of Medicine of Tunis University of Tunis el Manar Rabta Hospital  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6535-3286","authenticated-orcid":false,"given":"Santo","family":"Marsigliante","sequence":"additional","affiliation":[{"name":"Department of Biological and Environmental Science and Technologies (DiSTeBA) University of Salento  Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0971-0183","authenticated-orcid":false,"given":"Anissa","family":"Bouassida","sequence":"additional","affiliation":[{"name":"Research Unit \u201cSport Sciences Health and Movement\u201d (UR22JS01) High Institute of Sport and Physical Education of Kef University of Jendouba  Kef Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2412-9103","authenticated-orcid":false,"given":"Beat","family":"Knechtle","sequence":"additional","affiliation":[{"name":"Institute of Primary Care University Hospital of Zurich  Zurich Switzerland"},{"name":"Medbase St. Gallen Am Vadianplatz  St. Gallen Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2822-9929","authenticated-orcid":false,"given":"Antonella","family":"Muscella","sequence":"additional","affiliation":[{"name":"Department of Biological and Environmental Science and Technologies (DiSTeBA) University of Salento  Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_202305_32286"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1515\/hmbci\u20102020\u20100031"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu17010164"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26104753"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101648\u20104653"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768\u2010200009001\u201000009"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.2478\/jomb\u20102014\u20100057"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007\u20102329C"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/00365513.2017.1408140"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1515\/ssr\u20102015\u20100011"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640419408732181"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19010498"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256\u2010200333140\u201000002"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2010.179"},{"key":"e_1_2_13_16_1","first-page":"151","volume-title":"Field Tests to Evaluate Aerobic Capacity and Maximal Aerobic Speed","author":"Cazorla G.","year":"1990"},{"key":"e_1_2_13_17_1","volume-title":"Statistical Power Analysis for the Behavioural Sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768\u2010199112000\u201000004"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1974.37.4.521"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003677\u2010200104000\u201000009"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jesf.2018.11.003"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2024.1269508"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.12965\/jer.2142536.268"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2021.743935"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11886\u2010024\u201002036\u20103"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2024.1451427"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2016.11.022"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.31083\/j.fbl2811281"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1113\/EP091594"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25179706"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox11050894"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm\u20102012\u20100493"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13609"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2024.112664"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213\u20108587(22)00047\u2010X"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1982.52.5.1186"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.681"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2016.05.014"},{"issue":"2","key":"e_1_2_13_39_1","first-page":"77","article-title":"An Indirect Continuous Running Multistage Field Test: The Universit\u00e9 De Montr\u00e9al Track Test","volume":"5","author":"L\u00e9ger L.","year":"1980","journal-title":"Canadian Journal of Applied Sport Sciences"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.98"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17082955"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijsnem.18.5.457"},{"key":"e_1_2_13_43_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887\u2010021\u201003079\u2010z"},{"key":"e_1_2_13_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421\u2010015\u20103211\u2010z"},{"key":"e_1_2_13_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467\u2010789X.2011.00956.x"},{"key":"e_1_2_13_46_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102007\u20101024987"},{"key":"e_1_2_13_47_1","doi-asserted-by":"publisher","DOI":"10.1080\/02701367.1996.10607962"},{"key":"e_1_2_13_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/02640414.2024.2369447"},{"key":"e_1_2_13_49_1","doi-asserted-by":"publisher","DOI":"10.5604\/20831862.1198633"},{"key":"e_1_2_13_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/children10091495"},{"key":"e_1_2_13_51_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00833.2021"},{"key":"e_1_2_13_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2018.11.020"},{"key":"e_1_2_13_53_1","first-page":"712","volume-title":"Obesity","author":"Rossner S.","year":"1991"},{"key":"e_1_2_13_54_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2010.075341"},{"key":"e_1_2_13_55_1","doi-asserted-by":"publisher","DOI":"10.52082\/jssm.2024.690"},{"key":"e_1_2_13_56_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016\u20102573"},{"key":"e_1_2_13_57_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.850071"},{"key":"e_1_2_13_58_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2014.00380"},{"key":"e_1_2_13_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.04.042"},{"key":"e_1_2_13_60_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0022\u20104707.18.08075\u20101"},{"key":"e_1_2_13_61_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2025.1609818"},{"key":"e_1_2_13_62_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph191610401"},{"key":"e_1_2_13_63_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2025.1625516"},{"key":"e_1_2_13_64_1","doi-asserted-by":"publisher","DOI":"10.23736\/S0022\u20104707.20.11329\u2010X"},{"key":"e_1_2_13_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(07)61235\u20105"},{"key":"e_1_2_13_66_1","doi-asserted-by":"publisher","DOI":"10.1055\/a\u20101667\u20106624"}],"container-title":["European Journal of Sport Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejsc.70181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ejsc.70181","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ejsc.70181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T12:59:35Z","timestamp":1782737975000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ejsc.70181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":65,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/ejsc.70181"],"URL":"https:\/\/doi.org\/10.1002\/ejsc.70181","archive":["Portico"],"relation":{},"ISSN":["1746-1391","1536-7290"],"issn-type":[{"value":"1746-1391","type":"print"},{"value":"1536-7290","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"article-number":"e70181"}}