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However, findings regarding its effects on subsequent muscular strength and power remain inconsistent, and the participant\u2010 and protocol\u2010related characteristics associated with more favorable responses remain unclear. This systematic\u2010review and meta\u2010analysis aimed to evaluate the acute effects of ISO on subsequent muscular strength and power, compared ISO with control (CON) and dynamic isotonic contraction (DYN) conditions, and explore characteristics associated with more favorable PAPE. Twenty\u2010five studies involving 782 participants were included. A three\u2010level meta\u2010analysis was used to account for dependent effect sizes, complemented by moderator analyses and meta\u2010regression. For vertical jump height, ISO showed a significantly greater effect than CON (ES\u00a0=\u00a00.349,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.01), whereas no significant difference was detected between ISO and DYN; a significant pre\u2013post improvement was observed within the ISO group (ES\u00a0=\u00a00.180,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.01). No significant within\u2010ISO effect was observed for power output, and no significant effect was observed for muscular strength in either the within\u2010ISO or ISO versus CON comparison. Moderator and meta\u2010regression analyses suggested that some participant\u2010 and protocol\u2010related conditions were associated with larger subgroup\u2010specific effects on the vertical jump height, particularly 8\u201312\u00a0s contraction duration, 6\u201310 volume units, and 4\u20138\u00a0min of rest, although between\u2010level differences were generally inconsistent. ISO appears effective for eliciting PAPE in vertical jump height, whereas current evidence for muscular strength and power remains limited.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Protocol Registration<\/jats:title>\n                    <jats:p>The original protocol for the review was prospectively registered on PROSPERO (CRD42024608192)<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ejsc.70183","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:07:28Z","timestamp":1779257248000},"source":"Crossref","is-referenced-by-count":3,"title":["From Populations to Programming Variables: Post\u2010Activation Performance Enhancement Following Isometric Contractions on Muscular Strength and Power\u2014A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2613-2357","authenticated-orcid":false,"given":"Zhijian","family":"He","sequence":"first","affiliation":[{"name":"Department of Sports Teaching and Research Lanzhou University  Lanzhou China"},{"name":"School of Strength and Conditioning Training Beijing Sport University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhipeng","family":"Xue","sequence":"additional","affiliation":[{"name":"China Institute of Sport and Health Science Beijing Sport University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Qiang","sequence":"additional","affiliation":[{"name":"Ningxia Vocational College of Sports  Ningxia China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zepeng","family":"Lu","sequence":"additional","affiliation":[{"name":"Sports Coaching College Beijing Sport University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3891-9876","authenticated-orcid":false,"given":"Qiushi","family":"Wang","sequence":"additional","affiliation":[{"name":"Sports Coaching College Beijing Sport University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruinan","family":"Zhang","sequence":"additional","affiliation":[{"name":"China Institute of Sport and Health Science Beijing Sport University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilin","family":"Xu","sequence":"additional","affiliation":[{"name":"China Basketball College Beijing Sport University  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji","family":"Tu","sequence":"additional","affiliation":[{"name":"Institute of Basic Medical Sciences Chinese Academy of Medical Sciences School of Basic Medicine Peking Union Medical College  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dapeng","family":"Bao","sequence":"additional","affiliation":[{"name":"China Institute of Sport and Health Science Beijing Sport University  Beijing China"},{"name":"Medical Examination Center Peking University Third Hospital  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7931-7646","authenticated-orcid":false,"given":"Junhong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging Research Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768\u2010199808000\u201000006"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.88.1.35"},{"key":"e_1_2_14_4_1","doi-asserted-by":"crossref","unstructured":"Allen D. 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