{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T20:27:22Z","timestamp":1761596842237,"version":"build-2065373602"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Electrophoresis"],"published-print":{"date-parts":[[2004,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The fluorescence derivatizing agent, <jats:italic>o<\/jats:italic>\u2010phthalaldehyde (OPA), has been applied to the separation and detection of cyanide and several structurally similar thiols by capillary electrophoresis (CE)\u2010laser induced fluorescence (LIF). Of particular interest to this investigation was the separation of 2\u2010dimethylaminoethanethiol, 2\u2010diethylaminoethanethiol, and cyanide, each of which are hydrolysis products or hydrolysis product simulants of the chemical warfare (CW) agents <jats:italic>O<\/jats:italic>\u2010ethyl <jats:italic>S<\/jats:italic>\u20102\u2010diisopropylaminoethyl methylphosphonothiolate (VX), <jats:italic>O<\/jats:italic>\u2010isobutyl <jats:italic>S<\/jats:italic>\u20102\u2010diethylaminoethyl methylphosphonothiolate (R\u2010VX), and tabun (GA). Other structurally similar thiols simultaneously resolved by this method include 1\u2010pentanethiol and 2\u2010mercaptoethanol. Instrumental parameters were probed and optimum values for capillary length (50\u00a0cm) and inner diameter (75\u00a0\u03bcm), injection time (30 s) and field strength (15 kV) were determined. Sample stacking methods enabled detection limits of 9.3\u00a0\u03bcg\/L for cyanide, 1.8\u00a0\u03bcg\/L for 2\u2010diethylaminoethanethiol, 35\u00a0\u03bcg\/L for 2\u2010dimethylaminoethanethiol, 15\u00a0\u03bcg\/L for 2\u2010mercaptoethanol, and 89\u00a0\u03bcg\/L for 1\u2010pentanethiol. The linearity of\u00a0the method was verified over an order of magnitude and the reproducibility was found to be 3.0%.<\/jats:p>","DOI":"10.1002\/elps.200305775","type":"journal-article","created":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T20:17:57Z","timestamp":1078172277000},"page":"897-902","source":"Crossref","is-referenced-by-count":34,"title":["Separation of thiol and cyanide hydrolysis products of chemical warfare agents by capillary electrophoresis"],"prefix":"10.1002","volume":"25","author":[{"given":"Christine L.","family":"Copper","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Greg E.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,3]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00135a007"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(89)90346-1"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1039\/a608422b"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0039-9140(90)80152-6"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2670(97)00420-0"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2670(91)87144-V"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.17.649"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305710"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0308-8146(99)00227-7"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(98)00414-9"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ar970154s"},{"key":"e_1_2_1_13_2","unstructured":"Szafraniec L. 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