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The parameters that of affect the separation, such as the nature of the oil droplet and the buffer, and the surfactant concentration have been studied. In addition, several organic solvents were used to decrease the retention of the analytes in the oil droplet phase and to improve the resolution of the NSAIDs. The optimum microemulsion background electrolyte (BGE) solution made of 0.8%\u2005w\/w ethyl acetate, 6.6%\u2005w\/w butan\u20101\u2010ol, 6.0%\u2005w\/w acetonitrile, 1.0%\u2005w\/w sodium dodecyl sulfate (SDS), and 85.6%\u2005w\/w of 10\u2009m<jats:sc>M<\/jats:sc> sodium tetraborate at pH\u20059.2 resolved the drugs within 8\u2009min. The short\u2010end injection procedure is an alternative for reducing the analysis time. When this procedure was used, the microemulsion BGE solution consisted of 0.8%\u2005w\/w ethyl acetate, 6.6%\u2005w\/w butan\u20101\u2010ol, 17.0%\u2005w\/w methanol, 1.0%\u2005w\/w SDS, and 74.6%\u2005w\/w of 10\u2009m<jats:sc>M<\/jats:sc> sodium tetraborate, pH\u20059.2, and the NSAIDs were separated within 3\u2009min. The reversed electrode polarity stacking mode (REPSM) technique was applied to the on\u2010line concentration of the NSAIDs. In this technique, the sample matrix was pumped out of the capillary using a polarity\u2010switching step. When this technique was applied, the sensitivity was enhanced up to 40\u2010fold and the limits of detection (LODs) were in the low \u03bcg\u00b7L<jats:sup>\u20101<\/jats:sup> levels.<\/jats:p>","DOI":"10.1002\/elps.200410239","type":"journal-article","created":{"date-parts":[[2005,2,15]],"date-time":"2005-02-15T09:49:06Z","timestamp":1108460946000},"page":"970-979","source":"Crossref","is-referenced-by-count":39,"title":["Separation and on\u2010column preconcentration of some nonsteroidal anti\u2010inflammatory drugs by microemulsion electrokinetic capillary chromatography using high\u2010speed separations"],"prefix":"10.1002","volume":"26","author":[{"given":"Alba","family":"Maci\u00e0","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesc","family":"Borrull","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Calull","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carme","family":"Aguilar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,15]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(98)00217-9"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)00350-7"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)00088-1"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02491002"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-9936(01)00127-3"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200390041"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305637"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00021a020"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)00791-3"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2683(200105)22:7<1330::AID-ELPS1330>3.0.CO;2-D"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1039\/a800353j"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2683(200109)22:17<3819::AID-ELPS3819>3.0.CO;2-E"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1039\/b201226j"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02278600"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02292944"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02466572"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305875"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305793"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)00235-6"},{"key":"e_1_2_1_21_2","first-page":"223","volume":"4","author":"Quirino J.","year":"1997","journal-title":"J. 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