{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T18:21:34Z","timestamp":1781374894259,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,3,15]],"date-time":"2007-03-15T00:00:00Z","timestamp":1173916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Electrophoresis"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A simple and powerful microfluidic array chip\u2010based electrophoresis system, which is composed of a 3\u2010D microfluidic array chip, a microvacuum pump\u2010based negative pressure sampling device, a high\u2010voltage supply and an LIF detector, was developed. The 3\u2010D microfluidic array chip was fabricated with three glass plates, in which a common sample waste bus (SW<jats:sub>bus<\/jats:sub>) was etched in the bottom layer plate to avoid intersecting with the separation channel array. The negative pressure sampling device consists of a microvacuum air pump, a buffer vessel, a 3\u2010way electromagnet valve, and a vacuum gauge. In the sample loading step, all the six samples and buffer solutions were drawn from their reservoirs across the injection intersections through the SW<jats:sub>bus<\/jats:sub> toward the common sample waste reservoir (SW<jats:sub>T<\/jats:sub>) by negative pressure. Only 0.5\u2005s was required to obtain six pinched sample plugs at the channel crossings. By switching the three\u2010way electromagnetic valve to release the vacuum in the reservoir SW<jats:sub>T<\/jats:sub>, six sample plugs were simultaneously injected into the separation channels by EOF and electrophoretic separation was activated. Parallel separations of different analytes are presented on the 3\u2010D array chip by using the newly developed sampling device.<\/jats:p>","DOI":"10.1002\/elps.200600553","type":"journal-article","created":{"date-parts":[[2007,3,15]],"date-time":"2007-03-15T09:49:36Z","timestamp":1173952176000},"page":"1281-1288","source":"Crossref","is-referenced-by-count":17,"title":["Parallel separation of multiple samples with negative pressure sample injection on a 3\u2010D microfluidic array chip"],"prefix":"10.1002","volume":"28","author":[{"given":"Lei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefeng","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,4,2]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2683(20000101)21:1<41::AID-ELPS41>3.0.CO;2-7"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0202435"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305497"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac030051p"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac040063q"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac980349t"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0007938"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac961237"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.5.2256"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305818"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac990518p"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.012608699"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac020236g"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1039\/b501104c"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac990740u"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0485031"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200500283"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200500689"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00092a027"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac961093z"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac010138f"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2683(200101)22:2<363::AID-ELPS363>3.0.CO;2-G"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac025773f"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200500620"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1039\/b511924c"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00079a029"}],"container-title":["ELECTROPHORESIS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Felps.200600553","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/elps.200600553","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T09:07:50Z","timestamp":1760519270000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/elps.200600553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1002\/elps.200600553"],"URL":"https:\/\/doi.org\/10.1002\/elps.200600553","archive":["Portico"],"relation":{},"ISSN":["0173-0835","1522-2683"],"issn-type":[{"value":"0173-0835","type":"print"},{"value":"1522-2683","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}