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The results indicate that SI\u2010S\u2010\u03b2\u2010CD is an excellent chiral selector for enantioseparation of promethazine. The enantiomers of trimeprazine were well separated, while those of ethopropazine could also be baseline\u2010resolved with SI\u2010S\u2010\u03b2\u2010CD. With dual CD systems, especially with hydroxypropyl\u2010\u03b2\u2010CD (HP\u2010\u03b2\u2010CD) as neutral CD, the enantioselectivity of thioridazine and ethopropazine was considerably enhanced. Effective enantioseparation of phenothiazines, except for methotrimeprazine, could thus be favorably and simultaneously achieved. Moreover, reversal of the enantiomer migration order of ethopropazine and thioridazine occurred by varying the concentration of \u03b3\u2010CD in the presence of SI\u2010S\u2010\u03b2\u2010CD. These phenomena may be attributable to the opposite effects of sulfated \u03b2\u2010CD and \u03b3\u2010CD on the mobility of the enantiomers of ethopropazine and of thioridazine. Comparative studies on the enantioseparations of phenothiazines with single CD and dual CD systems containing SI\u2010S\u2010\u03b2\u2010CD and randomly sulfate\u2010substituted \u03b2\u2010CD (MI\u2010S\u2010\u03b2\u2010CD) were made.<\/jats:p>","DOI":"10.1002\/elps.200700059","type":"journal-article","created":{"date-parts":[[2007,10,5]],"date-time":"2007-10-05T12:17:27Z","timestamp":1191586647000},"page":"3922-3929","source":"Crossref","is-referenced-by-count":19,"title":["Enantioseparation of phenothiazines in CD\u2010modified CZE using single isomer sulfated CD as a chiral 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