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Stable and repeatable coating with good tolerance to 0.1\u2009M HCl, methanol, and ACN was obtained <jats:italic>via<\/jats:italic> a simple rinsing procedure. Au NPs enhanced the coating stability toward flushing by methanol, improved the run\u2010to\u2010run and capillary\u2010to\u2010capillary repeatabilities, and improved the separation efficiency of heroin and its basic impurities for tracing geographical origins of illicit samples. Baseline resolution of eight heroin\u2010related alkaloids was achieved on the PDDA\u2010protected Au NPs\u2010coated capillary under the optimum conditions: 120\u2009mM ammonium acetate (pH 5.2) with addition of 13% methanol, separation temperature 20\u00b0C, applied voltage \u221220\u2009kV, and capillary effective length 60.0\u2009cm. CE\u2010MS analysis with run\u2010to\u2010run RSDs (<jats:italic>n<\/jats:italic>=5) of migration time in the range of 0.43\u20130.62% and RSDs (<jats:italic>n<\/jats:italic>=5) of peak area in the range of 1.49\u20134.68% was obtained. The established CE\u2010MS method would offer sensitive detection and confident identification of heroin and related compounds and provide an alternative to LC\u2010MS and GC\u2010MS for illicit drug control.<\/jats:p>","DOI":"10.1002\/elps.200800069","type":"journal-article","created":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T15:37:14Z","timestamp":1230910634000},"page":"379-387","source":"Crossref","is-referenced-by-count":52,"title":["CE\u2010MS analysis of heroin and its basic impurities using a charged polymer\u2010protected gold nanoparticle\u2010coated capillary"],"prefix":"10.1002","volume":"30","author":[{"given":"Zhengxiang","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiping","family":"Liao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huwei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,2,9]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2787(1999)18:2<119::AID-MAS2>3.0.CO;2-Z"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2005.05.048"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/23.3.177"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1520\/JFS2003105"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1080\/00032710600668699"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.2449"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1556-4029.2006.00122.x"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1080\/00032710600755769"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(97)00384-8"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0112824"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/jms.921"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2005.05.048"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2006.02.047"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.05.023"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2004.01.062"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(95)00359-2"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(96)01999-1"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200390185"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200500078"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)00734-8"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0731-7085(03)00298-X"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)00659-7"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0379-0738(94)01612-9"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(95)00670-2"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9673(95)01311-3"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(97)00364-6"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(96)00773-X"},{"key":"e_1_2_6_29_2","first-page":"125","volume":"92","author":"Lurie I. 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