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An immobilization procedure was realized by prederivatization of the glass microchannel with (3\u2010mercaptopropyl)\u2010trimethoxysilane to provide thiol groups, which linked the BSA\u2010GNP conjugates on the inner surface of the microchannels. Incorporation of GNPs into immobilization of BSA selectors greatly increased the BSA phase ratio and favored the BSA stationary phase generated sufficient EOF. Good resolutions of FITC\u2010labeled ephedrine and norephedrine isomers were achieved with 36\u2009mm effective separation channel length within 250\u2009s. The constructed OT\u2010CEC microdevice exhibited good repeatabilities for run\u2010to\u2010run enantioseparations and kept an enantioselective lifetime of more than 1 month. The effects of pH values and concentrations of a running buffer on the selectivity and resolution of enantioseparations were investigated.<\/jats:p>","DOI":"10.1002\/elps.200800359","type":"journal-article","created":{"date-parts":[[2009,3,23]],"date-time":"2009-03-23T09:43:08Z","timestamp":1237801388000},"page":"1022-1029","source":"Crossref","is-referenced-by-count":75,"title":["Chip\u2010based enantioselective open\u2010tubular capillary electrochromatography using bovine serum albumin\u2010gold nanoparticle conjugates as the stationary phase"],"prefix":"10.1002","volume":"30","author":[{"given":"Hai\u2010Fang","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hulie","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifeng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Ming","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,23]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0202435"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac0202435"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2007.11.119"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200700150"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200700347"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2683(20000101)21:1<41::AID-ELPS41>3.0.CO;2-7"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305632"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305497"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-022X(02)00131-8"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.08.092"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(96)00769-8"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(99)01168-1"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00046a038"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.08.092"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200305640"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200500840"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac034452g"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac049313t"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200500884"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2005.09.030"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2005.07.020"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(98)00966-2"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00111a003"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2683(200107)22:12<2620::AID-ELPS2620>3.0.CO;2-D"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac000817a"},{"key":"e_1_2_6_27_2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.chroma.2004.04.056","volume":"1044","author":"Kato M.","journal-title":"J. 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