{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T18:30:15Z","timestamp":1764873015222,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T00:00:00Z","timestamp":1225152000000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Electrophoresis"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This paper introduces four different modes of multiple\u2010injection CZE (MICZE). The validity of these MICZE models was evaluated by the experimental data. Prior to the application of MICZE, the electrophoretic conditions are developed in the single\u2010injection mode by adjusting different experimental parameters such as pH, type and concentration of buffer additives and temperature. Based on the migration time difference (\u0394<jats:italic>t<\/jats:italic><jats:sub>mig<\/jats:sub>) between the analyte and the internal standard or injection marker, one or more MICZE modes can be employed. The injection marker is added to the sample to compensate for injection\u2010volume fluctuations. The inter\u2010plug distance is regulated by applying an electrical field over the capillary for a short period of time between each injection. After the final injection, the separation is completed by electrophoresis for a time period corresponding to that in the single\u2010injection mode.<\/jats:p>","DOI":"10.1002\/elps.200800398","type":"journal-article","created":{"date-parts":[[2008,10,28]],"date-time":"2008-10-28T02:52:11Z","timestamp":1225162331000},"page":"3952-3958","source":"Crossref","is-referenced-by-count":20,"title":["Principles for different modes of multiple\u2010injection CZE"],"prefix":"10.1002","volume":"29","author":[{"given":"Ahmad","family":"Amini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrik","family":"Lod\u00e9n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curt","family":"Pettersson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Torbj\u00f6rn","family":"Arvidsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,10,28]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"11","volume-title":"CE Methods for Pharmaceutical Analysis","author":"Lunn G.","year":"1999"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11094-006-0083-x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2006.01.035"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200600016"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00214a009"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2683(200109)22:15<3107::AID-ELPS3107>3.0.CO;2-Z"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-005-0047-0"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2005.10.062"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2006.03.039"},{"key":"e_1_2_6_11_2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/clinchem\/43.2.267","volume":"43","author":"Ulvik A.","year":"1997","journal-title":"Clin. 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