{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:02:21Z","timestamp":1791219741822,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,2,12]],"date-time":"2010-02-12T00:00:00Z","timestamp":1265932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Electrophoresis"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A generalized preparation procedure of open tubular (OT) molecule imprinted polymer (MIP) columns is proposed for a number of templates with acidic functionality such as profen drugs and others. The template (<jats:italic>S<\/jats:italic>\u2010enantiomer) was mixed with methacrylic acid, ethylene glycol dimethacrylate and 4\u2010styrenesulfonic acid, dissolved in a porogen mixture of ACN\/2\u2010propanol (9\/1), and incubated in a pretreated and silanized fused silica capillary by the thermal non\u2010covalent polymerization procedure. The whole preparation procedure was exactly the same for all the MIP capillaries except for the selection of template. Nevertheless, the morphologies of the MIP layers were markedly variant depending upon the choice of template. The separation efficiency of each OT\u2010MIP column for chiral separation of <jats:italic>R<\/jats:italic>\u2010 and <jats:italic>S<\/jats:italic>\u2010enantiomers was examined and tuned to obtain the best separation efficiency by changing the chromatographic parameters such as eluent composition and pH. Different optimized conditions were obtained for different OT\u2010MIP columns. Nevertheless, a unified eluent could be used to obtain still quite satisfactory results. Non\u2010chiral separation of the MIP columns were also examined in the unified eluent with two sets of test mixtures, that is, a mixture of alkylbenzenes and a mixture of small polar solutes. The chiral and non\u2010chiral separation of this study resulted in very good separation efficiencies. This work is the very first study for the generalization of preparation of OT\u2010MIP columns for a number of templates.<\/jats:p>","DOI":"10.1002\/elps.200900457","type":"journal-article","created":{"date-parts":[[2010,2,12]],"date-time":"2010-02-12T13:01:42Z","timestamp":1265979702000},"page":"1019-1028","source":"Crossref","is-referenced-by-count":49,"title":["Preparation of open tubular molecule imprinted polymer capillary columns with various templates by a generalized procedure and their chiral and non\u2010chiral separation performance in CEC"],"prefix":"10.1002","volume":"31","author":[{"given":"Shabi Abbas","family":"Zaidi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung Moon","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Guk","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Jo","family":"Cheong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2010,3,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)00532-X"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1081\/JLC-120030600"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.279"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/ac00056a028"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200390136"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.200400077"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2683(19990801)20:12<2313::AID-ELPS2313>3.0.CO;2-F"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-9244(01)80008-1"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.199518121"},{"key":"e_1_2_6_11_2","first-page":"166","volume":"2","author":"Shea K. 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