{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:46:08Z","timestamp":1760888768699,"version":"build-2065373602"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2013,6,5]],"date-time":"2013-06-05T00:00:00Z","timestamp":1370390400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Electrophoresis"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>The performance of high\u2010resolution <jats:styled-content style=\"fixed-case\">CZE<\/jats:styled-content> for determination of carbohydrate\u2010deficient transferrin (<jats:styled-content style=\"fixed-case\">CDT<\/jats:styled-content>) in human serum based on internal and external quality data gathered over a 10\u2010year period is reported. The assay comprises mixing of serum with a Fe(III) ion\u2010containing solution prior to analysis of the iron saturated mixture in a dynamically double\u2010coated capillary using a commercial buffer at alkaline pH. <jats:styled-content style=\"fixed-case\">CDT<\/jats:styled-content> values obtained with a human serum of a healthy individual and commercial quality control sera are shown to vary less than 10%. Values of a control from a specific lot were found to slowly decrease as function of time (less than 10% per year). Furthermore, due to unknown reasons, gradual changes in the monitored pattern around pentasialo\u2010transferrin were detected, which limit the use of commercial control sera of the same lot to less than 2 years. Analysis of external quality control sera revealed correct classification of the samples over the entire 10\u2010year period. Data obtained compare well with those of <jats:styled-content style=\"fixed-case\">HPLC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CZE<\/jats:styled-content> assays of other laboratories. The data gathered over a 10\u2010year period demonstrate the robustness of the high\u2010resolution <jats:styled-content style=\"fixed-case\">CZE<\/jats:styled-content> assay. This is the first account of a <jats:styled-content style=\"fixed-case\">CZE<\/jats:styled-content>\u2010based <jats:styled-content style=\"fixed-case\">CDT<\/jats:styled-content> assay with complete internal and external quality assessment over an extended time period.<\/jats:p>","DOI":"10.1002\/elps.201200653","type":"journal-article","created":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T04:23:03Z","timestamp":1363753383000},"page":"1563-1571","source":"Crossref","is-referenced-by-count":17,"title":["Determination of carbohydrate\u2010deficient transferrin in human serum by capillary zone electrophoresis: Evaluation of assay performance and quality assurance over a 10\u2010year period in the routine arena"],"prefix":"10.1002","volume":"34","author":[{"given":"Jeannine","family":"Joneli","sequence":"first","affiliation":[{"name":"Clinical Pharmacology Laboratory Institute for Infectious Diseases University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ursula","family":"Wanzenried","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Laboratory Institute for Infectious Diseases University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannette","family":"Schiess","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Laboratory Institute for Infectious Diseases University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Lanz","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Laboratory of Phytopharmacology Bioanalytics and Pharmacokinetics University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jitka","family":"Caslavska","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Laboratory Institute for Infectious Diseases University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Thormann","sequence":"additional","affiliation":[{"name":"Clinical Pharmacology Laboratory Institute for Infectious Diseases University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,6,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150090921"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/clinchem\/47.1.13","volume":"47","author":"Arndt T.","year":"2001","journal-title":"Clin. 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