{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:43:36Z","timestamp":1786977816780,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2013,7,15]],"date-time":"2013-07-15T00:00:00Z","timestamp":1373846400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Electrophoresis"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:p>\n                    Here, a simple micro free\u2010flow electrophoresis (\u03bcFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (\n                    <jats:italic>\u03bf<\/jats:italic>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">BBV<\/jats:styled-content>\n                    ) and fluorescent dye. The \u03bc\n                    <jats:styled-content style=\"fixed-case\">FFE<\/jats:styled-content>\n                    contained two open electrode cavities and an ion\u2010exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed \u03bc\n                    <jats:styled-content style=\"fixed-case\">FFE<\/jats:styled-content>\n                    : (i) up to 90.5% of voltage efficiency due to high conductivity of ion\u2010exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm \u00d7 17 mm \u00d7 100 \u03bcm, 77 \u03bcL) avoiding the discard of \u03bc\n                    <jats:styled-content style=\"fixed-case\">FFE<\/jats:styled-content>\n                    due to blockage of solute precipitation in chamber. Remarkably, the \u03bc\n                    <jats:styled-content style=\"fixed-case\">FFE<\/jats:styled-content>\n                    was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized\n                    <jats:italic>\u03bf<\/jats:italic>\n                    \u2010\n                    <jats:styled-content style=\"fixed-case\">BBV<\/jats:styled-content>\n                    , fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 \u00d7 10\n                    <jats:sup>\u221211<\/jats:sup>\n                    M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the \u03bc\n                    <jats:styled-content style=\"fixed-case\">FFE<\/jats:styled-content>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/elps.201300104","type":"journal-article","created":{"date-parts":[[2013,5,26]],"date-time":"2013-05-26T07:06:46Z","timestamp":1369552006000},"page":"2185-2192","source":"Crossref","is-referenced-by-count":9,"title":["A simple chip free\u2010flow electrophoresis for monosaccharide sensing via supermolecule interaction of boronic acid functionalized quencher and fluorescent dye"],"prefix":"10.1002","volume":"34","author":[{"given":"Xiao\u2010Yang","family":"Yin","sequence":"first","affiliation":[{"name":"Laboratory of Bio\u2010Separation and Analytical Biochemistry State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology Shanghai Jiao Tong University Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing\u2010Yu","family":"Dong","sequence":"additional","affiliation":[{"name":"Laboratory of Bio\u2010Separation and Analytical Biochemistry State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology Shanghai Jiao Tong University Shanghai P. R. China"},{"name":"Shanghai Key Laboratory of Functional Materials Chemistry East China University of Science and Technology Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hou\u2010Yu","family":"Wang","sequence":"additional","affiliation":[{"name":"Laboratory of Bio\u2010Separation and Analytical Biochemistry State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology Shanghai Jiao Tong University Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Bio\u2010Separation and Analytical Biochemistry State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology Shanghai Jiao Tong University Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu\u2010Yin","family":"Fan","sequence":"additional","affiliation":[{"name":"Laboratory of Bio\u2010Separation and Analytical Biochemistry State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology Shanghai Jiao Tong University Shanghai P. R. 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China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,7,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(89)71028-4"},{"key":"e_1_2_7_3_1","first-page":"388","volume":"19","author":"Stein G.","year":"1973","journal-title":"Biomedicine"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201100293"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.12.024"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.T600018-MCP200"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201100358"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150100302"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150110603"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac9025219"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150190712"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr0600632"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(94)00042-5"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150111111"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(97)01114-X"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201000162"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac00074a001"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150190704"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.1150191021"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200700725"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac00090a011"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac0345190"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1039\/b308476k"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac050766n"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200600137"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200800609"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201200169"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/45.9.1596"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac00030a001"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200701888"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja066567i"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2010.01.085"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2313(75)90003-4"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1039\/b514731j"}],"container-title":["ELECTROPHORESIS"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Felps.201300104","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/elps.201300104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:39:39Z","timestamp":1760524779000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/elps.201300104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7,15]]},"references-count":33,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["10.1002\/elps.201300104"],"URL":"https:\/\/doi.org\/10.1002\/elps.201300104","archive":["Portico"],"relation":{},"ISSN":["0173-0835","1522-2683"],"issn-type":[{"value":"0173-0835","type":"print"},{"value":"1522-2683","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,15]]}}}