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However, most of the studies so far were using magnetic microbead composed of nanosphere particle for magnetophoretic actuation purpose. Here, we developed an in\u2010house method for magnetic sample analysis called quadrupole magnetic steering control (QMSC). QMSC was used to study the magnetophoretic behavior of polystyrene microbeads decorated with iron oxide nanospheres\u2010coated polystyrene microbeads (IONSs\u2010PS) and iron oxide nanorods\u2010coated polystyrene microbeads (IONRs\u2010PS) under the influence of a quadrupole low field gradient. During a 4\u2010s QMSC experiment, the IONSs\u2010PS and IONRs\u2010PS were navigated to perform 180\u00b0 flip and 90\u00b0 turn formations, and their kinematic results (2\u00a0s before and 2\u00a0s after the flip\/turn) were measured and compared. The results showed that the IONRs\u2010PS suffered from significant kinematic disproportion, translating a highly uneven amount of kinetic energy from the same magnitude of magnetic control. Combining the kinematic analysis, transmission electron microscopy micrographs, and vibrating sample magnetometry measurements, it was found that the IONRs\u2010PS experienced higher fluid drag force and had lower consistency than the IONSs\u2010PS due to its extensive open fractal nanorod structure on the bead surface and uneven magnetization, which was attributed to its ferrimagnetic nature.<\/jats:p>","DOI":"10.1002\/elps.202300042","type":"journal-article","created":{"date-parts":[[2023,12,3]],"date-time":"2023-12-03T22:22:41Z","timestamp":1701642161000},"page":"357-368","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Navigating the microenvironment with flip and turn under quadrupole magnetophoretic steering control: Nanosphere\u2010 and nanorod\u2010coated microbead"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8707-0890","authenticated-orcid":false,"given":"Wai Hong","family":"Chong","sequence":"first","affiliation":[{"name":"School of Chemical Engineering Universiti Sains Malaysia  Nibong Tebal Penang Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek Juinn Chieh","family":"Chan","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering Universiti Sains Malaysia  Nibong Tebal Penang Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun\u2010Zhao","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Biochemical Engineering &amp; Key Laboratory of Green Process and Engineering, Institute of Process Engineering Chinese Academy of Sciences  Beijing P. 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