{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T17:08:54Z","timestamp":1764781734326},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2008,4,22]],"date-time":"2008-04-22T00:00:00Z","timestamp":1208822400000},"content-version":"vor","delay-in-days":6686,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environ and Mol Mutagen"],"published-print":{"date-parts":[[1990,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Frequencies of lymphocytes with micronuclei (MNF) in human peripheral blood cultures from workers in a sulphuric acid factory (the SO<jats:sub>2<\/jats:sub> concentrations in the workplace ranged from 0.34 mg\/m<jats:sup>3<\/jats:sup> to 11.97 mg\/m<jats:sup>3<\/jats:sup> air) were investigated. It was shown that among 40 workers, the MNF of 28 workers was more than 0.1 %, and the MNF of 7 workers was greater than the upper limit of the normal range (0.2%). The mean MNF of the worker and the control group was 0.168% and 0.071%, respectively. The difference between them was statistically significant (<jats:italic>P<\/jats:italic> &lt; 0.001). It implies that SO<jats:sub>2<\/jats:sub> is a clastogenic and genotoxic agent. No positive correlation between the MNF and length of service in workers has been observed. In the control population, the MNF of smokers was significantly higher than that of non\u2010smokers (<jats:italic>P<\/jats:italic> &lt; 0.001).<\/jats:p>","DOI":"10.1002\/em.2850150408","type":"journal-article","created":{"date-parts":[[2007,2,21]],"date-time":"2007-02-21T16:48:29Z","timestamp":1172076509000},"page":"218-220","source":"Crossref","is-referenced-by-count":23,"title":["Observation of frequencies of lymphocytes with micronuclei in human peripheral blood cultures from workers in a sulphuric acid factory"],"prefix":"10.1002","volume":"15","author":[{"given":"Ziqiang","family":"Meng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lianzhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,4,22]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000153664"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(76)90105-6"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/10520296509116440"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","unstructured":"MengZ ZhangL(1989):Chromosomal aberrations and sister\u2010chromatid exchanges in lymphocytes of workers exposed to sulphur dioxide. Mutat Res in press.","DOI":"10.1016\/0165-1218(90)90105-B"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5223.1980.tb01056.x"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-69530-8_11"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1967.71"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(70)90041-1"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-5223.1982.tb00724.x"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1139\/o62-025"}],"container-title":["Environmental and Molecular Mutagenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fem.2850150408","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/em.2850150408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T19:34:17Z","timestamp":1698003257000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/em.2850150408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["10.1002\/em.2850150408"],"URL":"https:\/\/doi.org\/10.1002\/em.2850150408","archive":["Portico"],"relation":{},"ISSN":["0893-6692","1098-2280"],"issn-type":[{"value":"0893-6692","type":"print"},{"value":"1098-2280","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}